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解读中国清火凉茶的配方奥秘。

Deciphering the Formulation Secret Underlying Chinese Huo-Clearing Herbal Drink.

作者信息

Wang Jianan, Zhou Bo, Hu Xiangdong, Dong Shuang, Hong Ming, Wang Jun, Chen Jian, Zhang Jiuliang, Zhang Qiyun, Li Xiaohua, Shikov Alexander N, Hu Sheng, Hu Xuebo

机构信息

Laboratory of Drug Discovery and Molecular Engineering, Department of Medicinal Plants, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, China.

National and Local Joint Engineering Research Center (Hubei) for Medicinal Plant Breeding and Cultivation, Wuhan, China.

出版信息

Front Pharmacol. 2021 Apr 22;12:654699. doi: 10.3389/fphar.2021.654699. eCollection 2021.

DOI:10.3389/fphar.2021.654699
PMID:33967798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8100228/
Abstract

Herbal teas or herbal drinks are traditional beverages that are prevalent in many cultures around the world. In Traditional Chinese Medicine, an herbal drink infused with different types of medicinal plants is believed to reduce the 'Shang Huo', or excessive body heat, a status of sub-optimal health. Although it is widely accepted and has a very large market, the underlying science for herbal drinks remains elusive. By studying a group of herbs for drinks, including 'Gan' ( Fisch. Ex DC.), 'Ju' ( (Ramat.) Tzvelev), 'Bu' ( L.), 'Jin' ( Thunb.), 'Xia' ( L.), and 'Ji' ( L.), the long-term jargon is connected with the inflammation of modern immunology through a few pro-inflammatory markers. studies have indicated that cellular inflammation is lowered by Ju and Jin either individually or synergistically with Gan. Among all herbs, only Gan detoxicated cellular toxicity of Bu in a dose dependent manner. The synergistic formulation of Ju and Gan, or Jin and Gan, in a reduction of Shang Huo, was tested . Both combinations exhibited a lower percentage of neutrophils, monocytes, and CD4/CD8 ratio in the blood, as well as inflammatory cytokines. Furthermore, body weight in the combinatory groups was more stable than treatments using single herbs. The combination of old traditional oriental methods with Western science logistics, has resulted in the formulation of different herbs into one concoction for the use of detoxification and synergism.

摘要

花草茶或草本饮料是世界各地许多文化中盛行的传统饮品。在传统中医中,一种由不同种类药用植物泡制的草本饮料被认为可以减轻“上火”,即身体过热,这是一种亚健康状态。尽管它被广泛接受且市场很大,但草本饮料背后的科学原理仍然难以捉摸。通过研究一组用于饮品的草药,包括“甘”( Fisch. Ex DC.)、“菊”( (Ramat.) Tzvelev)、“布”( L.)、“金”( Thunb.)、“夏”( L.)和“蓟”( L.),长期以来的术语通过一些促炎标志物与现代免疫学的炎症联系起来。研究表明,菊和金单独或与甘协同作用均可降低细胞炎症。在所有草药中,只有甘以剂量依赖的方式解毒布的细胞毒性。测试了菊和甘或金和甘协同配方在减轻上火方面的效果。两种组合在血液中均表现出较低百分比的中性粒细胞、单核细胞以及 CD4/CD8 比值,以及炎症细胞因子。此外,组合组的体重比使用单一草药的治疗组更稳定。将古老的传统东方方法与西方科学逻辑相结合,已促成将不同草药配制成一种混合物用于解毒和协同作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5812/8100228/7d53a3b065b4/fphar-12-654699-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5812/8100228/151501ddbcb0/fphar-12-654699-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5812/8100228/f5589ebf02fe/fphar-12-654699-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5812/8100228/62a5bb76fad4/fphar-12-654699-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5812/8100228/1ef99364fdad/fphar-12-654699-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5812/8100228/470acba3e4e2/fphar-12-654699-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5812/8100228/7d53a3b065b4/fphar-12-654699-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5812/8100228/151501ddbcb0/fphar-12-654699-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5812/8100228/f5589ebf02fe/fphar-12-654699-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5812/8100228/62a5bb76fad4/fphar-12-654699-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5812/8100228/1ef99364fdad/fphar-12-654699-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5812/8100228/470acba3e4e2/fphar-12-654699-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5812/8100228/7d53a3b065b4/fphar-12-654699-g006.jpg

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