Lee Hyun Jung, Kang Jeong Ho
Department of Physical Medicine and Rehabilitation, Jeju National University Hospital, Republic of Korea, Korea.
Department of Emergency Medicine, Jeju National University School of Medicine, Republic of Korea, Korea.
Turk J Emerg Med. 2021 Feb 12;21(2):82-85. doi: 10.4103/2452-2473.309136. eCollection 2021 Apr-Jun.
Glufosinate ammonium (GLA) is widely used as a commercial herbicide in many countries. Neurotoxicity of GLA has been associated with serious neurological complications such as loss of consciousness, convulsions, and memory impairment. Late-onset memory impairment due to GLA-induced hippocampal lesions is the most distinct clinical feature in GLA poisoning. However, the lesion of the splenium of the corpus callosum (SCC) is a rare condition in GLA poisoning, so the clinical features are not well known. We report the case of a 57-year-old male patient who developed SCC damage after GLA poisoning. The patient had various late-onset neurotoxic symptoms, including prolonged overall cognitive dysfunction and psychosis-like symptoms. Emergency physicians should be aware that GLA-induced SCC lesions may be associated with various late-onset neurotoxic symptoms.
草铵膦铵盐（GLA）在许多国家被广泛用作商业除草剂。GLA的神经毒性与严重的神经系统并发症有关，如意识丧失、抽搐和记忆障碍。GLA诱导的海马病变导致的迟发性记忆障碍是GLA中毒最明显的临床特征。然而，胼胝体压部（SCC）病变在GLA中毒中是一种罕见情况，因此其临床特征尚不为人所知。我们报告了一例57岁男性患者，其在GLA中毒后出现了SCC损伤。该患者出现了各种迟发性神经毒性症状，包括长期的整体认知功能障碍和类精神病症状。急诊医生应意识到，GLA诱导的SCC病变可能与各种迟发性神经毒性症状有关。
