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食蟹猴代谢、营养与肥胖

Marmoset Metabolism, Nutrition, and Obesity.

机构信息

Department of Life Sciences at Texas A&M University, San Antonio, Texas, USA.

Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.

出版信息

ILAR J. 2020 Dec 31;61(2-3):179-187. doi: 10.1093/ilar/ilab014.

Abstract

The use of marmosets as nonhuman primate models of human disease has undergone rapid expansion in the United States in the last decade, with an emphasis in the field of neuroscience. With this expanding need, there has been an increase in the formation of small marmoset colonies. The standardization in care and husbandry techniques for marmosets has historically lagged behind other established nonhuman primate models, resulting in a great deal of variation in practices between colonies. There remains a lack of consensus and evidence-based recommendations regarding best standards for nutrition, enrichment, weight management, and diagnostics for clinical metabolic disease. Marmoset base diets vary broadly in their nutritional value, and therefore the physiological responses to these diets also vary broadly. In this review, we briefly outline what is known about nutrition for captive marmosets and highlight what is known regarding metabolic dysfunction and obesity.

摘要

在过去十年中,美国将狨猴作为人类疾病的非人类灵长类动物模型的使用迅速扩大,神经科学领域尤为突出。随着这种需求的不断增长,狨猴小种群的数量也在不断增加。狨猴的护理和饲养技术的标准化在历史上落后于其他已建立的非人类灵长类动物模型,导致各个种群之间的实践存在很大差异。在营养、丰容、体重管理和临床代谢疾病诊断方面,仍然缺乏共识和基于证据的最佳标准推荐。圈养狨猴的基础饮食在营养价值上差异很大,因此对这些饮食的生理反应也差异很大。在这篇综述中,我们简要概述了圈养狨猴的营养状况,并强调了代谢功能障碍和肥胖症的相关知识。

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