Department of Radiology, Alder Hey Children's NHS Foundation Trust, East Prescot Road, Liverpool, L14 5AB, UK.
Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
Childs Nerv Syst. 2021 Aug;37(8):2497-2508. doi: 10.1007/s00381-021-05199-4. Epub 2021 May 10.
Standardisation of imaging acquisition is essential in facilitating multicentre studies related to childhood CNS tumours. It is important to ensure that the imaging protocol can be adopted by centres with varying imaging capabilities without compromising image quality.
An imaging protocol has been developed by the Brain Tumour Imaging Working Group of the European Society for Paediatric Oncology (SIOPE) based on consensus among its members, which consists of neuroradiologists, imaging scientists and paediatric neuro-oncologists. This protocol has been developed to facilitate SIOPE led studies and regularly reviewed by the imaging working group.
The protocol consists of essential MRI sequences with imaging parameters for 1.5 and 3 Tesla MRI scanners and a set of optional sequences that can be used in appropriate clinical settings. The protocol also provides guidelines for early post-operative imaging and surveillance imaging. The complementary use of multimodal advanced MRI including diffusion tensor imaging (DTI), MR spectroscopy and perfusion imaging is encouraged, and optional guidance is provided in this publication.
The SIOPE brain tumour imaging protocol will enable consistent imaging across multiple centres involved in paediatric CNS tumour studies.
在促进与儿童中枢神经系统肿瘤相关的多中心研究中，成像采集的标准化至关重要。重要的是要确保成像协议可以被具有不同成像能力的中心采用，而不会影响图像质量。
欧洲小儿肿瘤学会（SIOPE）的脑肿瘤成像工作组的成员基于共识制定了一个成像协议，该协议由神经放射科医生、成像科学家和小儿神经肿瘤学家组成。该协议旨在促进 SIOPE 领导的研究，并由成像工作组定期审查。
该协议包括基本的 MRI 序列和用于 1.5 和 3 Tesla MRI 扫描仪的成像参数，以及一组可在适当临床环境中使用的可选序列。该协议还为术后早期成像和监测成像提供了指南。鼓励使用多模态高级 MRI 进行互补，包括弥散张量成像（DTI）、磁共振波谱和灌注成像，并在本出版物中提供了可选指导。
SIOPE 脑肿瘤成像协议将使参与儿童中枢神经系统肿瘤研究的多个中心能够进行一致的成像。
