Department of Internal Medicine, Dell Medical School at University of Texas at Austin, Austin, Texas.
Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md.
J Allergy Clin Immunol Pract. 2021 Sep;9(9):3290-3292. doi: 10.1016/j.jaip.2021.04.063. Epub 2021 May 8.
An evolving body of literature links chemicals commonly found in personal care products (PCPs) to an increased risk of both developing asthma and worsening existing asthma. Phthalates, parabens, environmental phenols, such as triclosan and bisphenol A, and other endocrine-disrupting compounds have been implicated in asthma and related allergic conditions in epidemiological studies. Because Black individuals have increased exposure to these chemicals through hair care products and feminine hygiene products, disproportionate exposure to these chemicals through PCPs could contribute, in part, to the disproportionate asthma prevalence and morbidity among the U.S. Black population. Increased exposure to these chemicals among Black individuals is explained, in part, by more frequent use of hair care products that can contain higher concentrations of these chemicals and greater use of feminine hygiene products, which are also sources of exposure to these chemicals. Epidemiological evidence using urinary biomarkers of exposure demonstrates associations between PCPs and exposure to these chemicals and that the U.S. Black population has greater exposure to these chemicals than the non-Black population. Should chemical exposures through PCPs contribute to the excess burden of asthma among the U.S. Black population, reducing these exposures would reduce this disparity.
越来越多的文献将个人护理产品（PCP）中常见的化学物质与哮喘的发病风险增加和现有哮喘的恶化联系起来。邻苯二甲酸酯、对羟基苯甲酸酯、环境酚类物质（如三氯生和双酚 A）和其他内分泌干扰化合物在流行病学研究中与哮喘和相关过敏状况有关。由于黑人通过护发产品和女性卫生产品接触到这些化学物质的几率增加，因此通过 PCP 接触到这些化学物质的不成比例的暴露可能是导致美国黑人中哮喘患病率和发病率不成比例的部分原因。黑人接触这些化学物质的风险增加部分是由于他们更频繁地使用护发产品，这些产品可能含有更高浓度的这些化学物质，并且更频繁地使用女性卫生产品，这些产品也是接触这些化学物质的来源。使用尿液生物标志物进行的流行病学证据表明，PCP 和接触这些化学物质之间存在关联，并且美国黑人接触这些化学物质的程度高于非黑人人口。如果通过 PCP 接触化学物质导致美国黑人哮喘负担过重，那么减少这些暴露将减少这种差异。
