School of Public and Community Health Sciences, University of Montana, Missoula, Montana.
School of Public and Community Health Sciences, University of Montana, Missoula, Montana.
Am J Prev Med. 2021 Jul;61(1):e21-e29. doi: 10.1016/j.amepre.2021.01.038. Epub 2021 May 8.
Early childhood vaccination rates are lower in rural areas than those in urban areas of the U.S. This study's objective is to quantify vaccine timeliness and the prevalence of undervaccination patterns in Montana and to measure the associations between timeliness and series completion by age 24 months.
Using records from January 2015 to November 2019 in Montana's centralized immunization information system, days undervaccinated were calculated for the combined 7-vaccine series. Undervaccination patterns indicative of certain barriers to vaccination, including parental vaccine hesitancy, were identified. Using multivariable log-linked binomial regression, the association between timing of vaccine delay and not completing the combined 7-vaccine series by age 24 months was assessed. Analyses were conducted in March 2020-August 2020.
Among 31,422 children, 38.0% received all vaccine doses on time; 24.3% received all doses, but some were received late; and 37.7% had not completed the combined 7-vaccine series. Approximately 18.7% had an undervaccination pattern suggestive of parental vaccine hesitancy, and 19.7% started all series but were missing doses needed for multidose series completion. Although falling behind on vaccinations at any age was associated with failing to complete the combined 7-vaccine series, being late at age 12-15 months had the strongest association (adjusted prevalence ratio=3.73, 95% CI=3.56, 3.91) compared with being on time at age 12-15 months.
Fewer than 2 in 5 Montana children were fully vaccinated on time for the combined 7-vaccine series. To increase vaccination rates, initiatives to increase vaccine confidence and remind parents to complete vaccine series are needed.
美国农村地区的儿童疫苗接种率低于城市地区。本研究旨在量化蒙大拿州疫苗接种的及时性和未完全接种的流行情况,并测量 24 月龄时疫苗接种及时性与完成系列接种之间的关联。
使用蒙大拿州集中免疫信息系统 2015 年 1 月至 2019 年 11 月的记录,计算了 7 联疫苗系列中每剂疫苗的延误天数。确定了一些表明存在疫苗接种障碍的未完全接种模式,包括父母对疫苗的犹豫。使用多变量对数链接二项式回归评估 24 月龄时疫苗延迟接种与未完成 7 联疫苗系列之间的关联。分析于 2020 年 3 月至 8 月进行。
在 31422 名儿童中,38.0%按时接种了所有疫苗;24.3%按时接种了所有疫苗,但有些疫苗接种延迟;37.7%未完成 7 联疫苗系列接种。大约 18.7%的儿童存在表明父母对疫苗犹豫不决的未完全接种模式,19.7%开始了所有系列接种,但缺少完成多剂量系列所需的剂量。尽管任何年龄段的疫苗接种落后都与未完成 7 联疫苗系列接种有关,但 12-15 月龄时延迟接种与按时接种相比,与未完成 7 联疫苗系列接种的关联最强(调整后流行率比=3.73,95%置信区间=3.56,3.91)。
不到 2/5 的蒙大拿州儿童按时完全接种了 7 联疫苗系列。为了提高疫苗接种率,需要采取提高疫苗信心和提醒家长完成疫苗系列接种的措施。