Aortic Institute at Yale New-Haven, Yale University School of Medicine, New Haven, CT, USA; Department of General Surgery, Istishari Hospital, Amman, Jordan.
Aortic Institute at Yale New-Haven, Yale University School of Medicine, New Haven, CT, USA.
Semin Thorac Cardiovasc Surg. 2022 Summer;34(2):419-427. doi: 10.1053/j.semtcvs.2021.04.002. Epub 2021 May 9.
We examined the long-term fate of the preserved aortic root after emergent repair of acute Type A aortic dissection. 144 patients (60% males, mean age 60.5 years) underwent supracoronary ascending aortic replacement for acute Type A aortic dissection. Long-term survival, as well as growth, reoperation, and adverse events of the aortic root (rupture, pseudoaneurysm, and persistent dissection) were retrospectively assessed. Operative mortality was 9%, and overall survival at 1, 5, and 10 years was 87.8%, 76.4%, and 64.6%, respectively. Reoperation on the proximal aorta was performed in 16 patients (12.2%) within a median of 2.45 years post-operatively. Indications were severe aortic insufficiency (AI) (n = 6), aortic root pseudoaneurysm (n = 8), pseudoaneurysm with severe AI (n = 1), and persistent dissection with severe AI (n = 1). The aortic root grew at 0.2mm/year (interquartile range 0-0.8). Among survivors (n = 131), 28 patients (21.3%) reached aortic root diameter ≥ 45 mm (mean diameter 47.6 mm, range 45-54 mm). Survival free from proximal aortic reoperation at 1, 5, and 10 years was 96.6%, 94.5%, and 92.2%, respectively. No non-reoperated patient-despite persistent, unoperated enlargement or distortion or pseudoaneurysm of the aortic root-developed free rupture or fistula to a cardiac chamber. Root-sparing ascending aortic replacement for acute Type-A aortic dissection showed satisfactory long-term outcomes with relatively low rates of re-intervention or serious aortic root adverse events despite dilatation and irregularity of aortic root contour. Dense adhesions from prior surgery, proximal aortic suture line, and Teflon felt seem to discourage free rupture or fistulization.
我们研究了急性 A 型主动脉夹层急诊修复后主动脉根部的长期转归。144 例患者(60%为男性,平均年龄 60.5 岁)因急性 A 型主动脉夹层行升主动脉根部上方冠状动脉置换术。回顾性评估主动脉根部的长期生存、生长、再次手术和不良事件(破裂、假性动脉瘤和持续性夹层)。手术死亡率为 9%,术后 1、5 和 10 年的总生存率分别为 87.8%、76.4%和 64.6%。16 例患者(12.2%)在术后中位时间 2.45 年内再次行升主动脉近端手术。手术指征为严重主动脉瓣关闭不全(AI)(n=6)、主动脉根部假性动脉瘤(n=8)、严重 AI 合并假性动脉瘤(n=1)和持续性 AI 合并严重 AI(n=1)。主动脉根部每年增长 0.2mm(四分位间距 0-0.8)。在存活患者(n=131)中,28 例(21.3%)主动脉根部直径≥45mm(平均直径 47.6mm,范围 45-54mm)。1、5 和 10 年无近端主动脉再次手术的生存率分别为 96.6%、94.5%和 92.2%。尽管主动脉根部轮廓存在扩张和不规则,但无未经手术的患者发生主动脉根部破裂或瘘至心腔。对于急性 A 型主动脉夹层,行保留主动脉根部的升主动脉置换术可获得满意的长期结果,再次干预或严重主动脉根部不良事件的发生率相对较低。由于先前手术、近端主动脉缝线和特氟隆毡的致密粘连,可能会阻止主动脉根部的自由破裂或瘘化。