De Vleeschhauwer Joni, Broeder Sanne, Janssens Luc, Heremans Elke, Nieuwboer Alice, Nackaerts Evelien
KU Leuven, Department of Rehabilitation Sciences Research Group for Neurorehabilitation (eNRGy) Leuven Belgium.
KU Leuven, Group T Campus, Electrical Engineering Technology (ESAT) Leuven Belgium.
Mov Disord Clin Pract. 2021 Mar 12;8(4):546-554. doi: 10.1002/mdc3.13179. eCollection 2021 May.
Deficits in fine motor skills may impair device manipulation including touchscreens in people with Parkinson's disease (PD).
To investigate the impact of PD and anti-parkinsonian medication on the ability to use touchscreens.
Twelve PD patients (H&Y II-III), OFF and ON medication, and 12 healthy controls (HC) performed tapping, single and multi-direction sliding tasks on a touchscreen and a mobile phone task (MPT). Task performance was compared between patients (PD-OFF, PD-ON) and HC and between medication conditions.
Significant differences were found in touchscreen timing parameters, while accuracy was comparable between groups. PD-OFF needed more time than HC to perform single ( = 0.048) and multi-direction ( = 0.004) sliding tasks and to grab the dot before sliding (i.e., transition times) ( = 0.040; = 0.004). For tapping, dopaminergic medication significantly increased performance times ( = 0.046) to comparable levels as those of HC. However, for the more complex multi-direction sliding, movement times remained slower in PD than HC irrespective of medication intake ( < 0.050 during ON and OFF). The transition times for the multi-direction sliding task was also higher in PD-ON than HC ( = 0.048). Touchscreen parameters significantly correlated with MPT performance, supporting the ecological validity of the touchscreen tool.
PD patients show motor problems when manipulating touchscreens, even when optimally medicated. This hinders using mobile technology in daily life and has implications for developing adequate E-health applications for this group. Future work needs to establish whether touchscreen training is effective in PD.
帕金森病（PD）患者的精细运动技能缺陷可能会损害包括触摸屏操作在内的设备操控能力。
研究帕金森病及其抗帕金森药物对使用触摸屏能力的影响。
12名帕金森病患者（H&Y II-III级），分别处于未服药和服药状态，以及12名健康对照者（HC），在触摸屏上执行点击、单方向和多方向滑动任务以及一项手机任务（MPT）。比较患者（未服药的PD患者、服药的PD患者）与健康对照者之间以及不同服药状态下的任务表现。
在触摸屏计时参数方面发现了显著差异，而各组之间的准确性相当。未服药的PD患者在执行单方向（P = 0.048）和多方向（P = 0.004）滑动任务以及在滑动前抓取点（即转换时间）（P = 0.040；P = 0.004）时比健康对照者需要更多时间。对于点击任务，多巴胺能药物显著增加了执行时间（P = 0.046），使其达到与健康对照者相当的水平。然而，对于更复杂的多方向滑动任务，无论服药与否，帕金森病患者的移动时间仍然比健康对照者慢（服药和未服药时P均<0.050）。服药的PD患者在多方向滑动任务中的转换时间也高于健康对照者（P = 0.048）。触摸屏参数与手机任务表现显著相关，支持了触摸屏工具的生态效度。
帕金森病患者即使在最佳药物治疗状态下，在操作触摸屏时也存在运动问题。这阻碍了他们在日常生活中使用移动技术，并且对为该群体开发适当的电子健康应用具有启示意义。未来的工作需要确定触摸屏训练对帕金森病患者是否有效。
