Department of Biochemistry, All India Institute of Medical Sciences (AIIMS), Deoghar, Jharkhand, 814 142, India.
Formerly, Department of Medical Biochemistry, University of Madras, Taramani Campus, Chennai, India.
Mol Biol Rep. 2021 Apr;48(4):3733-3745. doi: 10.1007/s11033-021-06367-0. Epub 2021 May 14.
Phenolic compounds, present in plants, are considered to be indispensable parts of human dietary sources. Sinapic acid, is a natural herbal compound containing phenolic acid. It is found in oranges, grapefruits, and cranberries and in herbs like canola, mustard seed and rapeseed. Sinapic acid is chemically studied as a cinnamic acid derivative that contains 3, 5-dimethoxyl and 4-hydroxyl substitutions in the phenyl group of cinnamic acid. Sinapic acid has been pharmacologically evaluated for its potent antioxidant, anti-inflammatory, anti-cancer, hepatoprotective, cardioprotective, renoprotective, neuroprotective, anti-diabetic, anxiolytic and anti-bacterial activities. In this review we have summarized the potential pharmacological and therapeutic effects of Sinapic acid in various models.
酚类化合物存在于植物中，被认为是人类饮食来源中不可或缺的一部分。芥子酸是一种天然草本化合物，含有酚酸。它存在于橙子、葡萄柚和蔓越莓中，以及油菜籽、芥菜籽和油菜籽等草药中。芥子酸在化学上被研究为肉桂酸的衍生物，它在肉桂酸的苯环上含有 3、5-二甲氧基和 4-羟基取代基。芥子酸因其具有强大的抗氧化、抗炎、抗癌、保肝、护心、肾保护、神经保护、抗糖尿病、抗焦虑和抗菌活性而在药理学上得到了评估。在这篇综述中，我们总结了芥子酸在各种模型中的潜在药理和治疗作用。
