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口腔颌面部骨肉瘤(成骨肉瘤)——四例系列报告。

Osteosarcoma (osteogenic sarcoma) of the jaws presenting in general dental practice - a series of four cases.

机构信息

Oral and Maxillofacial Surgery, St James's Hospital, Dublin 8, Ireland.

Consultant in Oral Histopathology, St James's Hospital, Dublin 8, Ireland.

出版信息

Br Dent J. 2021 May;230(9):583-586. doi: 10.1038/s41415-021-2943-x. Epub 2021 May 14.

Abstract

Introduction Osteosarcoma is the most common primary malignant bone tumour, usually arising in the long bones, with occurrence in the head and neck accounting for 8% of all osteosarcomas. Clinical features include swelling, pain, facial dysesthesia and abnormal mobility of teeth. Treatment consists of a combination of surgery, radiotherapy and chemotherapy.Case series Here, we present four cases of osteosarcoma of the jaws - two maxillary and two mandibular. All cases were initially assessed in the dental primary care setting before being referred for specialist opinion.Discussion The purpose of this paper is to present an overview of an uncommon but serious disease which can mimic common life-threatening dento-facial conditions. We discuss the diagnostic features, with an overview of clinical, histopathological and radiographic features.Conclusion These cases are important reminders of the potential clinical and radiographic appearance of a rare cause of facial swelling, and highlight the role of the general dental practitioner in early diagnosis and referral.

摘要

引言:成骨肉瘤是最常见的原发性恶性骨肿瘤,通常发生于长骨,头颈部的发生率占所有成骨肉瘤的 8%。临床特征包括肿胀、疼痛、面部感觉异常和牙齿异常活动。治疗包括手术、放疗和化疗的综合应用。

病例系列:在这里,我们介绍了 4 例颌骨成骨肉瘤,2 例上颌骨,2 例下颌骨。所有病例最初均在牙科初级保健机构进行评估,然后转介至专家处。

讨论:本文旨在介绍一种不常见但严重的疾病,该疾病可模拟常见的危及生命的齿面状况。我们讨论了诊断特征,并概述了临床、组织病理学和影像学特征。

结论:这些病例提醒人们注意一种罕见的面部肿胀的潜在临床和影像学表现,并且突出了普通牙医在早期诊断和转诊中的作用。

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