Department of Biotechnology, National Institute of Technology, Raipur, CG, India.
Drug Deliv Transl Res. 2022 May;12(5):968-972. doi: 10.1007/s13346-021-01001-9. Epub 2021 May 15.
The years 2020 and 2021 have witnessed a COVID-19 pandemic caused by the SARS-CoV-2 virus. However, these years have also witnessed certain remarkable scientific achievements. Researchers across the globe have been trying extremely hard and accomplished in bringing vaccines a great variety of COVID-19 vaccines. Though the route of administration for the majority of these vaccines has been the intramuscular route (invasive), some laboratories are developing formulations intended for transmucosal and transcutaneous (non-invasive) administration, which are in the early phases of pre-clinical and clinical development. This short report discusses these unconventional formulations against COVID-19, in brief, to stress the importance of research in the field of drug delivery.
2020 年和 2021 年见证了由 SARS-CoV-2 病毒引起的 COVID-19 大流行。然而，这两年也见证了一些显著的科学成就。全球的研究人员一直在努力，取得了多种 COVID-19 疫苗的成果。虽然这些疫苗的大部分给药途径都是肌内途径（侵入性），但一些实验室正在开发用于黏膜和经皮（非侵入性）给药的制剂，这些制剂处于临床前和临床开发的早期阶段。本简短报告简要讨论了这些针对 COVID-19 的非传统制剂，以强调药物输送领域研究的重要性。
