Ganesan Abirami Ramu, Balasubramanian Balamuralikrishnan, Park Sungkwon, Jha Rajesh, Andretta Ines, Bakare Archibold G, Kim In Ho
Department of Food Science and Home Economics, School of Applied Sciences, College of Engineering, Science and Technology, Fiji National University, Suva, Fiji Islands.
Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, South Korea.
Anim Nutr. 2021 Mar;7(1):56-63. doi: 10.1016/j.aninu.2020.06.006. Epub 2020 Dec 31.
This review aims to highlight the effects of ochratoxin A (OTA) in the feed of meat-producing animals. The accumulation of OTA in feed and its distribution in various farm animals were compared and evaluated. Primarily, the oral administration of OTA-contaminated feed and the predisposition in an animal's vital organ were critically examined in this work. The collated reports show that OTA directly associated with endemic nephropathy and its high concentration leads to degeneration of liver cells, and necrosis of intestinal and lymphoid tissues. At present, limited reports are available in the recent literature on the problems and consequences of OTA in feed. Therefore, this review focused on the OTA carryover from feed to farm animals and the interaction of its secondary metabolites on their biochemical parameters. Hence, this report provides greater insights into animal health related to OTA residues in meat and meat products. This article also explores mitigation strategies that can be used to prevent the carryover effects of OTA in livestock feeds and the effects in the food chain.
本综述旨在强调肉用动物饲料中赭曲霉毒素A（OTA）的影响。对OTA在饲料中的积累及其在各类农场动物中的分布进行了比较和评估。主要地，在本研究中对口服受OTA污染的饲料以及动物重要器官中的易感性进行了严格审查。整理后的报告表明，OTA与地方性肾病直接相关，其高浓度会导致肝细胞变性以及肠道和淋巴组织坏死。目前，近期文献中关于饲料中OTA的问题和后果的报道有限。因此，本综述聚焦于OTA从饲料到农场动物的残留以及其次级代谢产物对动物生化参数的影响。因此，本报告为与肉类和肉制品中OTA残留相关的动物健康提供了更深入的见解。本文还探讨了可用于预防OTA在牲畜饲料中的残留影响及其在食物链中的影响的缓解策略。
