DDS Diagnostic, Bucharest, Romania.
Faculty of Medicine, Titu Maiorescu University, Bucharest, Romania.
Exp Dermatol. 2021 Sep;30(9):1218-1232. doi: 10.1111/exd.14396. Epub 2021 Jun 7.
Although superficial wounds are often easy to treat for healthy individuals, there are some more severe types of wounds (burns, ulcers, diabetic wounds, etc.) that are a challenge for clinicians. A good therapeutic result is based on the delivery of a treatment at the right time, for the right patient. Our goal was to sum up useful knowledge regarding wound healing and wound treatments, based on creams and hydrogels with various active ingredients. We concluded that both preparations have application in preventing infections and promoting healing, but their efficacy is clearly conditioned by the type, depth, severity of the wound and patient profile. However, due to their superior versatility and capability of maintaining the integrity and functionality of the active ingredient, as well as it is controlled release at site, hydrogels are more suited for incorporating different active ingredients. New wound healing devices can combine smart hydrogel dressings with physical therapies to deliver a more efficient treatment to patients if the indications are appropriate.
虽然对于健康个体来说，浅表伤口通常很容易治疗，但有些更严重类型的伤口（烧伤、溃疡、糖尿病伤口等）对临床医生来说是一个挑战。良好的治疗效果基于在正确的时间为正确的患者提供治疗。我们的目标是根据含有各种活性成分的乳膏和水凝胶，总结有关伤口愈合和伤口处理的有用知识。我们得出的结论是，这两种制剂都可用于预防感染和促进愈合，但它们的疗效显然取决于伤口的类型、深度、严重程度和患者特征。然而，由于水凝胶具有更好的多功能性和保持活性成分完整性和功能性的能力，以及其在作用部位的控制释放，因此更适合加入不同的活性成分。如果适应证合适，新型伤口愈合装置可以将智能水凝胶敷料与物理疗法相结合，为患者提供更有效的治疗。
