• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

南非来源牛暂时热病毒疫苗株的基因组序列。

Genome sequence of Bovine Ephemeral fever virus vaccine strain of South African origin.

机构信息

Ondersterpoort Biological Products, Onderstepoort, South Africa.

出版信息

Vet Med Sci. 2021 Sep;7(5):1611-1615. doi: 10.1002/vms3.517. Epub 2021 May 20.

DOI:10.1002/vms3.517
PMID:34015189
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8464265/
Abstract

Bovine Ephemeral fever virus (BEFV) is endemic in South Africa and has a negative economic impact on the meat and dairy industries. Bovine ephemeral fever or three-day stiff-sickness is controlled through annual vaccination with a live attenuated virus manufactured by Onderstepoort Biological Products (South Africa). We announce the genome sequences of two South African Bovine Ephemeral Virus strains; the live attenuated vaccine strain (14 876 nucleotides) and a field strain (14 883 nucleotides). A mutation in the alpha 3 open reading frame rendered the gene non-functional in both genomes. Phylogenetic analysis based on the glycoprotein gene showed that the two strains clustered with the South African lineage.

摘要

牛暂时热病毒（BEFV）在南非流行，对肉类和奶制品行业造成了负面影响。通过使用由 Onderstepoort 生物制品（南非）生产的减毒活疫苗对牛进行年度接种，可以控制牛暂时热或三天僵病。我们宣布了两个南非牛暂时热病毒株的基因组序列；减毒活疫苗株（14876 个核苷酸）和田间株（14883 个核苷酸）。α3 开放阅读框中的突变使两个基因组中的基因失去功能。基于糖蛋白基因的系统发育分析表明，这两个菌株与南非谱系聚类。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c1/8464265/519f00caebab/VMS3-7-1611-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c1/8464265/0c242ed7768a/VMS3-7-1611-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c1/8464265/519f00caebab/VMS3-7-1611-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c1/8464265/0c242ed7768a/VMS3-7-1611-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c1/8464265/519f00caebab/VMS3-7-1611-g001.jpg

相似文献

1
Genome sequence of Bovine Ephemeral fever virus vaccine strain of South African origin.南非来源牛暂时热病毒疫苗株的基因组序列。
Vet Med Sci. 2021 Sep;7(5):1611-1615. doi: 10.1002/vms3.517. Epub 2021 May 20.
2
Molecular characterization of bovine ephemeral fever virus in Thailand between 2013 and 2017.2013 年至 2017 年期间泰国流行热病毒的分子特征。
Vet Microbiol. 2018 Dec;227:1-7. doi: 10.1016/j.vetmic.2018.10.013. Epub 2018 Oct 15.
3
Complete genome sequencing and assessment of mutation-associated protein dynamics of the first Indian bovine ephemeral fever virus (BEFV) isolate.完整基因组测序及首个印度牛暂时热病毒（BEFV）分离株突变相关蛋白动力学评估。
Vet Q. 2021 Dec;41(1):308-319. doi: 10.1080/01652176.2021.1995909.
4
South African bovine ephemeral fever virus glycoprotein sequences are phylogenetically distinct from those from the rest of the world.南非牛暂时热病毒糖蛋白序列与世界其他地区的序列在系统发生上是不同的。
Arch Virol. 2020 May;165(5):1207-1210. doi: 10.1007/s00705-020-04568-9. Epub 2020 Mar 5.
5
Bovine ephemeral fever in Australia and the world.澳大利亚及全球的牛流行热
Curr Top Microbiol Immunol. 2005;292:57-80. doi: 10.1007/3-540-27485-5_4.
6
Genetic characterization of bovine ephemeral fever virus in southern China, 2013-2017.2013 - 2017年中国南方牛流行热病毒的基因特征分析
Virus Genes. 2020 Jun;56(3):390-395. doi: 10.1007/s11262-020-01740-w. Epub 2020 Feb 6.
7
Isolation and genetic characterization of bovine ephemeral fever virus from epidemic-2020 in Turkey.从 2020 年土耳其流行疫情中分离鉴定到牛暂时热病毒。
Trop Anim Health Prod. 2021 Apr 21;53(2):276. doi: 10.1007/s11250-021-02715-1.
8
Whole genome characterization and evolutionary analysis of bovine ephemeral fever virus isolated in Iran.伊朗分离的牛暂时热病毒的全基因组特征和进化分析。
Arch Microbiol. 2023 Apr 16;205(5):196. doi: 10.1007/s00203-023-03527-7.
9
Epidemiology and control of bovine ephemeral fever.牛流行热的流行病学与防控
Vet Res. 2015 Oct 28;46:124. doi: 10.1186/s13567-015-0262-4.
10
Phylogenetic relationships of the G gene sequence of bovine ephemeral fever virus isolated in Japan, Taiwan and Australia.在日本、台湾和澳大利亚分离出的牛暂时热病毒G基因序列的系统发育关系。
Vet Microbiol. 2009 Jun 12;137(3-4):217-23. doi: 10.1016/j.vetmic.2009.01.021. Epub 2009 Jan 20.

引用本文的文献

1
Coinfection of Bovine ephemeral fever virus and 'Candidatus Mycoplasma haemobos' in cattle in Central China: implications for tick-borne transmission and viral divergence.中国中部地区牛感染牛流行热病毒和“嗜血性牛支原体（暂定种）”的共感染：对蜱传播及病毒分化的影响
BMC Vet Res. 2025 Jul 12;21(1):460. doi: 10.1186/s12917-025-04917-3.
2
Whole genome characterization and evolutionary analysis of bovine ephemeral fever virus isolated in Iran.伊朗分离的牛暂时热病毒的全基因组特征和进化分析。
Arch Microbiol. 2023 Apr 16;205(5):196. doi: 10.1007/s00203-023-03527-7.
3
Molecular characterization and phylogenetic analysis of bovine ephemeral fever viruses in Khuzestan province of Iran in 2018 and 2020.

本文引用的文献

1
Identification and phylogenetic characterization of bovine ephemeral fever virus (BEFV) of Middle Eastern lineage associated with 2018-2019 outbreaks in India.与2018 - 2019年印度疫情相关的中东谱系牛暂时热病毒（BEFV）的鉴定及系统发育特征分析
Transbound Emerg Dis. 2020 Sep;67(5):2226-2232. doi: 10.1111/tbed.13531. Epub 2020 Mar 24.
2
South African bovine ephemeral fever virus glycoprotein sequences are phylogenetically distinct from those from the rest of the world.南非牛暂时热病毒糖蛋白序列与世界其他地区的序列在系统发生上是不同的。
Arch Virol. 2020 May;165(5):1207-1210. doi: 10.1007/s00705-020-04568-9. Epub 2020 Mar 5.
3
2018 年和 2020 年伊朗胡齐斯坦省牛暂时热病毒的分子特征和系统进化分析。
BMC Vet Res. 2022 Jan 6;18(1):19. doi: 10.1186/s12917-021-03119-x.
4
The Development of Dual Vaccines against Lumpy Skin Disease (LSD) and Bovine Ephemeral Fever (BEF).抗结节性皮肤病（LSD）和牛流行热（BEF）双价疫苗的研发
Vaccines (Basel). 2021 Oct 20;9(11):1215. doi: 10.3390/vaccines9111215.
Cell apoptosis regulated by interaction between viral gene alpha 3 and host heterogeneous nuclear ribonucleoprotein K facilitates bovine ephemeral fever virus replication.
病毒基因α 3 与宿主异质核核糖核蛋白 K 的相互作用调控细胞凋亡，促进牛暂时热病毒复制。
Vet Microbiol. 2020 Jan;240:108510. doi: 10.1016/j.vetmic.2019.108510. Epub 2019 Nov 15.
4
Co-circulation and characterization of novel African arboviruses (genus Ephemerovirus) in cattle, Mayotte island, Indian Ocean, 2017.2017 年，印度洋马约特岛牛群中新型非洲虫媒病毒（属暂定型病毒）的共同传播和特征描述。
Transbound Emerg Dis. 2019 Nov;66(6):2601-2604. doi: 10.1111/tbed.13323. Epub 2019 Aug 27.
5
Complete genome sequence of a bovine ephemeral fever virus JT02L strain in mainland China.中国大陆牛暂时热病毒JT02L株的全基因组序列
Arch Virol. 2017 Nov;162(11):3555-3558. doi: 10.1007/s00705-017-3520-0. Epub 2017 Aug 14.
6
MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets.MEGA7：适用于更大数据集的分子进化遗传学分析版本7.0
Mol Biol Evol. 2016 Jul;33(7):1870-4. doi: 10.1093/molbev/msw054. Epub 2016 Mar 22.
7
Bovine Ephemeral Fever in Iran: Diagnosis, Isolation and Molecular Characterization.伊朗的牛流行热：诊断、分离及分子特征分析
J Arthropod Borne Dis. 2015 Mar 11;9(2):195-203. eCollection 2015 Dec.
8
Epidemiology and control of bovine ephemeral fever.牛流行热的流行病学与防控
Vet Res. 2015 Oct 28;46:124. doi: 10.1186/s13567-015-0262-4.
9
Phylogenetic relationships of the glycoprotein gene of bovine ephemeral fever virus isolated from mainland China, Taiwan, Japan, Turkey, Israel and Australia.中国大陆、台湾、日本、土耳其、以色列和澳大利亚分离的牛暂时热病毒糖蛋白基因的系统进化关系。
Virol J. 2012 Nov 14;9:268. doi: 10.1186/1743-422X-9-268.
10
Studies on the development of a vaccine against bovine ephemeral fever.牛流行热疫苗研发研究。
Onderstepoort J Vet Res. 1973 Sep;40(3):77-82.