Wood James, Reagan Krystle L, Gunther-Harrington Catherine, Sykes Jane E
William R Pritchard Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA.
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA.
JFMS Open Rep. 2021 May 11;7(1):20551169211012346. doi: 10.1177/20551169211012346. eCollection 2021 Jan-Jun.
A 3-year-old neutered male domestic mediumhair cat was evaluated for a 4-month history of a fever that was responsive to pradofloxacin. A grade III/VI left parasternal systolic heart murmur was noted on examination. Findings on thoracic radiography were consistent with left-sided congestive heart failure and findings on echocardiographic examination suggested endomyocarditis. Aerobic blood cultures yielded growth of a species that was identified as using both matrix-associated laser desorption ionization-time of flight mass spectrometry and 16S rRNA gene sequencing. The cat was treated but clinically deteriorated and was euthanized 23 days after diagnosis.
To our knowledge, this is the first report of bacteremia, an emerging pathogen, in association with endomyocarditis in the cat. This case also highlights the role of echocardiography to document progressive hemodynamic changes as a result of valvular erosion in the course of infective endocarditis treatment and the role of blood cultures as a diagnostic tool in cats presenting with fever.
一只3岁已绝育的雄性家养中毛猫因持续4个月的发热接受评估，该发热对普拉德氟沙星有反应。检查时发现左侧胸骨旁有III/VI级收缩期心脏杂音。胸部X线检查结果与左侧充血性心力衰竭一致，超声心动图检查结果提示心内膜炎。需氧血培养培养出一种细菌，通过基质辅助激光解吸电离飞行时间质谱法和16S rRNA基因测序鉴定该细菌。这只猫接受了治疗，但临床病情恶化，诊断后23天实施安乐死。
据我们所知，这是首例关于猫感染新兴病原体[细菌名称未给出]菌血症并伴有心内膜炎的报告。该病例还凸显了超声心动图在记录感染性心内膜炎治疗过程中瓣膜侵蚀导致的血流动力学渐进性变化方面的作用，以及血培养在出现发热症状的猫中的诊断工具作用。
