Ben Abid Fatma, El-Maki Nada, Alsoub Hussam, Al Masalmani Muna, Al-Khal Abdullatif, Valentine Coyle Peter, Ben Hadj Kacem Mohamed Ali, AlGazwani Hafedh, Al-Thani Mohammed, Eid Al-Romaihi Hamad, Al-Hajri Mohammed, Elmoubashar Farag
Department of Medicine, Division of Infectious Diseases, Hamad Medical Corporation, Doha, Qatar.
Weill Cornell Medical College, Doha, Qatar.
IDCases. 2021;24:e01161. doi: 10.1016/j.idcr.2021.e01161. Epub 2021 May 17.
The Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012. The objective of the study was to describe the epidemiology, risk factors, clinical characteristics, and outcome of MERS-CoV in Qatar. A total of 28 cases of MERS-CoV were identified, corresponding to an incidence of 1.7 per 1,000,000 population. Most patients had a history of contact with camels 15, travel to Kingdom of Saudi Arabia 7 or known contact with individuals with confirmed MERS-CoV infection 7. Majority of patients had acute kidney injury (AKI) 17 and 9 needed renal replacement therapy. All patients were hospitalized, 14 required critical care support. Overall, total of 10 died. The immediate cause of death was multiorgan failure with acute respiratory syndrome (ARDS) 9. MERS-CoV is a rare infection in the State of Qatar. There was no hospital outbreaks or healthcare worker reported infection. The infection causes severe respiratory failure and acute renal failure. Patients with AKI and on ventilator support carry higher risk of mortality.
中东呼吸综合征冠状病毒（MERS-CoV）于2012年出现。本研究的目的是描述卡塔尔MERS-CoV的流行病学、危险因素、临床特征及转归。共确诊28例MERS-CoV病例，发病率为每100万人口1.7例。大多数患者有接触骆驼史（15例）、前往沙特阿拉伯王国史（7例）或已知接触确诊MERS-CoV感染个体史（7例）。大多数患者发生急性肾损伤（AKI）（17例），9例需要肾脏替代治疗。所有患者均住院治疗，14例需要重症监护支持。总体而言，共有10例死亡。直接死因是多器官功能衰竭合并急性呼吸窘迫综合征（ARDS）（9例）。MERS-CoV在卡塔尔国是一种罕见感染。未报告医院暴发或医护人员感染情况。该感染可导致严重呼吸衰竭和急性肾衰竭。发生AKI且需要呼吸机支持的患者死亡风险更高。
