Dropsy Hélène, Cozar Alicia, De Jaeger Xavier, Billy Charlotte, Noli Chiara, Cristante Romain, Leymarios Florence, Deschamps Véronique, Gatellet Marina
Department of Dermatology, National Veterinary School of Alfort, Maisons-Alfort, France.
Ceva Santé Animale, Libourne, France.
J Feline Med Surg. 2025 Apr;27(4):1098612X251324174. doi: 10.1177/1098612X251324174. Epub 2025 Apr 16.
ObjectivesThe application of Ophytrium and chlorhexidine (DOUXO S3 PYO Shampoo and Pads; Ceva Santé Animale) in cats for managing cutaneous microbial imbalances was analysed.MethodsClient-owned cats with microbiota imbalance characterised by overgrowth, bacterial overgrowth or both were recruited. The cats were either washed with shampoo, when possible, considering the localisation of the affected zones and the cooperation of the cat, or treated with topical pads on day 0 (D0), and then received daily pad applications for either 2 weeks (D14) or 3 weeks (D21). Microorganisms were assessed on D0, D7, D14 and D21 using quantitative cytological counts, and pruritus was graded by the owner using a pruritus visual analogue scale for cats (VAScat). Satisfaction questionnaires were collected from both the veterinarians and owners on D14 and D21 (end of follow-up [EOF]).ResultsAmong the 10 cats that completed the study, cytological resolution, defined as a mean number of bacteria per oil immersion field (OIF) ⩽2 and/or a mean number of yeasts per OIF ⩽1, occurred on D7 and at EOF in 60% and 90% of animals, respectively. Median yeast count per OIF decreased significantly from D0 (6.7) to EOF (0.0). Similarly, the median bacterial count decreased significantly from D0 (18.0) to EOF (0.0). Median highest values assigned using the VAScat decreased significantly from D0 (4.3) to EOF (1.4). Overall, the veterinarians assessed the cytological and clinical improvement as satisfactory, good or excellent in nine cases. The protocol was considered efficient and practical by nine (90%) owners and the pads were considered easy to use by all 10 (100%) owners.Conclusions and relevancePads and an optional shampoo containing Ophytrium and chlorhexidine were well tolerated. These products were effective in achieving cytological resolution and improving clinical signs and discomfort in cats with microbiota disturbances, yielding high satisfaction levels in veterinarians and owners.
目的
分析奥菲癣菌和洗必泰（DOUXO S3 PYO洗发水和护理垫；法国诗华动物保健公司）在猫身上用于管理皮肤微生物失衡的应用情况。
方法
招募患有微生物群失衡（特征为过度生长、细菌过度生长或两者皆有）的客户拥有的猫。根据受影响区域的位置和猫的配合情况，尽可能用洗发水给猫洗澡，或者在第0天（D0）用护理垫进行治疗，然后每天使用护理垫，持续2周（D14）或3周（D21）。在D0、D7、D14和D21使用定量细胞学计数评估微生物，并由主人使用猫瘙痒视觉模拟量表（VAScat）对瘙痒进行分级。在D14和D21（随访结束[EOF]）收集兽医和主人的满意度问卷。
结果
在完成研究的10只猫中，细胞学缓解定义为每个油镜视野（OIF）的细菌平均数⩽2和/或每个OIF的酵母平均数⩽1，分别在D7和随访结束时出现在60%和90% 的动物中。每个OIF的酵母中位数从D0（6.7）显著下降到随访结束时（0.0）。同样，细菌中位数从D0（18.0）显著下降到随访结束时（0.0）。使用VAScat分配的最高中位数从D0（4.3）显著下降到随访结束时（1.4）。总体而言，兽医评估9例猫的细胞学和临床改善为满意、良好或优秀。9名（90%）主人认为该方案有效且实用，所有10名（100%）主人认为护理垫易于使用。
结论及相关性
含有奥菲癣菌和洗必泰的护理垫和可选洗发水耐受性良好。这些产品有效地实现了细胞学缓解，并改善了微生物群紊乱猫的临床症状和不适，在兽医和主人中获得了很高的满意度。
