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亚马逊西部地区的乳腺癌和宫颈癌死亡率:1980年至2014年的时间序列研究。

Breast and cervical cancer mortality in the western Amazon: A time series study between 1980 and 2014.

作者信息

Leitão Francisco Naildo Cardoso, Bezerra Italla Maria Pinheiro, de Lima Marcos Vinicius Malveira, Pimentel Renata Macedo Martins, Jr Hugo Macedo, Morais Mauro José de Deus, Machado Ana Paula Araújo, Abreu Luiz Carlos de

机构信息

Study Design and Scientific Writing Laboratory (LaDEEC/ABC) Health University Center.

Study and Scientific Writing Multidisciplinary Laboratory in Heath Sciences (LAMEECCS/UFAC), Acrel.

出版信息

Medicine (Baltimore). 2021 May 28;100(21):e26157. doi: 10.1097/MD.0000000000026157.

Abstract

Among the main types of neoplasms in the female population, breast and cervical cancers are the most important due to their high morbidity and mortality rates. The mortality has been proportionally higher in developing countries. Analysis of the trend of cancer mortality in Brazil revealed a considerable difference in the pattern of deaths between the regions.To analyze the trend of mortality due to breast and cervical cancers in women.Retrospective study of a series of death cases, using secondary data from the mortality information system (SIM) of the Ministry of Health. The deaths were identified as the underlying cause of breast and cervical cancers, including malignant neoplasms of the uterus without other specifications, occurring from 1980 to 2014. Thus, the annual standardized age-specific mortality rates by the world population were applied. For trend analysis, regression models were utilized in which the mortality rates were considered dependent variables and years the independent variable. Polynomial regression models and a Prais-Winsten regression model were adopted.Cervical cancer presented a mortality rate ranging from 2.15 to 10.69 per 100,000 women from 1980 to 2014, with a tendency for stability.Breast cancer mortality rate varied from 3.81 to 11.47 per 100,000 women from 1981 to 2014, indicating a growing trend.There is a significant increase in the mortality rate for breast cancer and stability of cervical cancers in the State of Acre from 1980 to 2014, evidencing a concern in their care and monitoring. Above all, guaranteed access, especially to the population of women at social risk, and the search for effective screening should be emphasized in the formation of the care line and the Health Care Network in the State of Acre.

摘要

在女性人群的主要肿瘤类型中,乳腺癌和宫颈癌因其高发病率和死亡率而最为重要。在发展中国家,死亡率相对更高。对巴西癌症死亡率趋势的分析显示,各地区的死亡模式存在显著差异。为分析女性乳腺癌和宫颈癌的死亡率趋势。采用卫生部死亡率信息系统(SIM)的二手数据,对一系列死亡病例进行回顾性研究。这些死亡被确定为乳腺癌和宫颈癌的根本原因,包括未作其他说明的子宫恶性肿瘤,发生时间为1980年至2014年。因此,应用了按世界人口计算的年度标准化年龄别死亡率。为进行趋势分析,使用了回归模型,其中死亡率被视为因变量,年份被视为自变量。采用了多项式回归模型和普雷斯-温斯顿回归模型。1980年至2014年,宫颈癌的死亡率为每10万名女性2.15至10.69人,呈稳定趋势。1981年至2014年,乳腺癌的死亡率为每10万名女性3.81至11.47人,呈上升趋势。1980年至2014年,阿克里州乳腺癌死亡率显著上升,宫颈癌死亡率稳定,这表明在其护理和监测方面令人担忧。最重要的是,在阿克里州护理线路和医疗保健网络的形成中,应强调确保获得医疗服务,特别是对处于社会风险中的女性人群,并寻求有效的筛查方法。

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