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巴西年轻女性乳腺癌死亡率上升:趋势分析

The Rise in Mortality from Breast Cancer in Young Women: Trend Analysis in Brazil.

作者信息

Rocha-Brischiliari Sheila Cristina, Oliveira Rosana Rosseto de, Andrade Luciano, Brischiliari Adriano, Gravena Angela Andreia França, Carvalho Maria Dalva de Barros, Pelloso Sandra Marisa

机构信息

Health Science Center, State University of Maringa, Maringa, Parana, Brazil.

Department of Nursing, State University of Maringa, Maringa, Parana, Brazil.

出版信息

PLoS One. 2017 Jan 3;12(1):e0168950. doi: 10.1371/journal.pone.0168950. eCollection 2017.

DOI:10.1371/journal.pone.0168950
PMID:28046087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5207532/
Abstract

INTRODUCTION

Breast cancer is the most common cause of cancer death among women.

OBJECTIVE

The objective of this study was to analyze time trends in overall mortality from breast cancer in Brazil, Brazilian regions and States.

METHODS

This is an exploratory study, of the time series of deaths from breast cancer contained in the Mortality Information System (SIM), of women living in Brazil, Brazilian regions and States, from 1996 to 2013. For the trend analysis, the polynomial regression model was used, and a significant trend was considered when the estimated model obtained a p value <0.05.

RESULTS

There was a tendency of increased mortality from breast cancer in Brazilian women (average increase of 0.18 per year; p <0.001), with regional differences, particularly in the age group 20-49 years (0.07 per year; p <0.001). The age group 50-69 years remained constant but had high average rates (37.14).

CONCLUSION

More effective planning is needed to focus on the different scenarios of the Brazilian regions. Screening strategies for the incidence and mortality from breast cancer must also be rethought according to age group in the country.

摘要

引言

乳腺癌是女性癌症死亡的最常见原因。

目的

本研究的目的是分析巴西、巴西各地区和各州乳腺癌总体死亡率的时间趋势。

方法

这是一项探索性研究,对1996年至2013年居住在巴西、巴西各地区和各州的女性的乳腺癌死亡时间序列进行研究。对于趋势分析,使用多项式回归模型,当估计模型的p值<0.05时,认为存在显著趋势。

结果

巴西女性乳腺癌死亡率呈上升趋势(平均每年上升0.18;p<0.001),存在地区差异,尤其是在20-49岁年龄组(每年0.07;p<0.001)。50-69岁年龄组保持稳定,但平均死亡率较高(37.14)。

结论

需要进行更有效的规划,以关注巴西各地区的不同情况。还必须根据该国的年龄组重新思考乳腺癌发病率和死亡率的筛查策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c790/5207532/31a3b5c87f20/pone.0168950.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c790/5207532/0e3669a37e2a/pone.0168950.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c790/5207532/95497aba9dd1/pone.0168950.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c790/5207532/31a3b5c87f20/pone.0168950.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c790/5207532/0e3669a37e2a/pone.0168950.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c790/5207532/95497aba9dd1/pone.0168950.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c790/5207532/31a3b5c87f20/pone.0168950.g003.jpg

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