Zwain Ahmed, Aldiwani Mohanad, Taqi Hussein
North West Deanery, Aintree University Hospital Liverpool, UK.
East Midlands Deanery, University Hospitals of Leicester NHS Trust Leicester, UK.
Eur Cardiol. 2021 May 13;16:e19. doi: 10.15420/ecr.2020.15.R2. eCollection 2021 Feb.
Cardiovascular diseases and psoriasis have been well established as separate entities, however, there is uncertainty with regards to a link between the two diseases. A few environmental, psychological and social factors have been implicated as potential common risk factors that may exacerbate the two diseases, and an array of complex immune and non-immune inflammatory mediators can potentially explain a plausible link. Pharmacotherapy has also played a role in establishing a potential association, especially with the advent of biological agents which directly act on inflammatory factors shared by the two diseases. This review will look at existing evidence and ascertain a potential correlation between the two.
心血管疾病和银屑病已被明确为两种独立的疾病，然而，这两种疾病之间的联系尚不确定。一些环境、心理和社会因素被认为是可能加剧这两种疾病的潜在共同风险因素，一系列复杂的免疫和非免疫炎症介质可能解释了一种合理的联系。药物治疗也在建立潜在关联方面发挥了作用，特别是随着直接作用于这两种疾病共有的炎症因子的生物制剂的出现。本综述将审视现有证据并确定两者之间的潜在相关性。
