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INTELLiVENT-自适应支持通气在 ICU 患者中应用的效果、安全性和疗效 - 系统评价。

Effectiveness, safety and efficacy of INTELLiVENT-adaptive support ventilation, a closed-loop ventilation mode for use in ICU patients - a systematic review.

机构信息

Department of Intensive Care, Amsterdam University Medical Centers, Location 'AMC', Amsterdam, The Netherlands.

Department of Intensive Care, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.

出版信息

Expert Rev Respir Med. 2021 Nov;15(11):1403-1413. doi: 10.1080/17476348.2021.1933450. Epub 2021 Jul 31.

DOI:10.1080/17476348.2021.1933450
PMID:34047244
Abstract

: INTELLiVENT-Adaptive Support Ventilation (INTELLiVENT-ASV), an advanced closed-loop ventilation mode for use in intensive care unit (ICU) patients, is equipped with algorithms that automatically adjust settings on the basis of physiologic signals and patient's activity. Here we describe its effectiveness, safety, and efficacy in various types of ICU patients.: A systematic search conducted in MEDLINE, EMBASE, the Cochrane Central register of Controlled Trials (CENTRAL), and in Google Scholar identified 10 randomized clinical trials.: Studies suggest INTELLiVENT-ASV to be an effective automated mode with regard to the titrations of tidal volume, airway pressure, and oxygen. INTELLiVENT-ASV is as safe as conventional modes. However, thus far studies have not shown INTELLiVENT-ASV to be superior to conventional modes with regard to duration of ventilation and other patient-centered outcomes. Future studies are needed to test its efficacy.

摘要

: INTELLiVENT-自适应支持通气(INTELLiVENT-ASV)是一种先进的闭环通气模式,用于重症监护病房(ICU)患者,配备了根据生理信号和患者活动自动调整设置的算法。在这里,我们描述了它在各种类型的 ICU 患者中的有效性、安全性和疗效。: 在 MEDLINE、EMBASE、Cochrane 中央对照试验注册中心(CENTRAL)和 Google Scholar 中进行了系统搜索,共确定了 10 项随机临床试验。: 研究表明,在潮气量、气道压力和氧合的滴定方面,INTELLiVENT-ASV 是一种有效的自动模式。INTELLiVENT-ASV 与传统模式一样安全。然而,迄今为止的研究并未表明 INTELLiVENT-ASV 在通气时间和其他以患者为中心的结局方面优于传统模式。需要进一步的研究来检验其疗效。

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