Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.
MathSys CDT, University of Warwick, Coventry, UK.
Philos Trans R Soc Lond B Biol Sci. 2021 Jul 19;376(1829):20200270. doi: 10.1098/rstb.2020.0270. Epub 2021 May 31.
Contact tracing is an important tool for allowing countries to ease lockdown policies introduced to combat SARS-CoV-2. For contact tracing to be effective, those with symptoms must self-report themselves while their contacts must self-isolate when asked. However, policies such as legal enforcement of self-isolation can create trade-offs by dissuading individuals from self-reporting. We use an existing branching process model to examine which aspects of contact tracing adherence should be prioritized. We consider an inverse relationship between self-isolation adherence and self-reporting engagement, assuming that increasingly strict self-isolation policies will result in fewer individuals self-reporting to the programme. We find that policies which increase the average duration of self-isolation, or that increase the probability that people self-isolate at all, at the expense of reduced self-reporting rate, will not decrease the risk of a large outbreak and may increase the risk, depending on the strength of the trade-off. These results suggest that policies to increase self-isolation adherence should be implemented carefully. Policies that increase self-isolation adherence at the cost of self-reporting rates should be avoided. This article is part of the theme issue 'Modelling that shaped the early COVID-19 pandemic response in the UK'.
接触者追踪是允许各国放宽为应对 SARS-CoV-2 而实施的封锁政策的重要工具。为了使接触者追踪有效,有症状的人必须自行报告,而其接触者必须在被要求时自我隔离。然而,诸如隔离的法律执行等政策可能会通过劝阻个人自我报告而产生权衡。我们使用现有的分支过程模型来检查应优先考虑接触者追踪遵守的哪些方面。我们假设自我隔离遵守和自我报告参与之间存在反比关系,即越来越严格的自我隔离政策将导致向该计划报告的个人减少。我们发现,以减少自我报告率为代价,增加自我隔离平均持续时间或增加所有人自我隔离的可能性的政策,不会降低大规模爆发的风险,并且可能会增加风险,具体取决于权衡的强度。这些结果表明,应谨慎实施增加自我隔离遵守的政策。应避免以降低自我报告率为代价来增加自我隔离遵守率的政策。本文是“塑造英国 COVID-19 大流行早期应对措施的模型”专题的一部分。