Bionanomechanics Lab, Instituto de Micro y Nanotecnología, IMN-CNM (CSIC), Isaac Newton 8 (PTM), E-28760 Tres Cantos, Madrid, Spain.
Sensors (Basel). 2021 May 11;21(10):3337. doi: 10.3390/s21103337.
In this work we study the different phenomena taking place when a hydrostatic pressure is applied in the inner fluid of a suspended microchannel resonator. Additionally to pressure-induced stiffness terms, we have theoretically predicted and experimentally demonstrated that the pressure also induces mass effects which depend on both the applied pressure and the fluid properties. We have used these phenomena to characterize the frequency response of the device as a function of the fluid compressibility and molecular masses of different fluids ranging from liquids to gases. The proposed device in this work can measure the mass density of an unknown liquid sample with a resolution of 0.7 µg/mL and perform gas mixtures characterization by measuring its average molecular mass with a resolution of 0.01 atomic mass units.
在这项工作中，我们研究了在悬浮微通道谐振器内部流体中施加静水压力时发生的不同现象。除了压力引起的刚度项之外，我们还从理论上预测并实验证明，压力还会引起质量效应，这些质量效应既取决于所施加的压力，又取决于流体的性质。我们利用这些现象来描述器件的频率响应作为不同流体（从液体到气体）的可压缩性和分子质量的函数。本工作中提出的器件可以测量未知液体样品的质量密度，分辨率为 0.7 µg/mL，通过测量其平均分子量来实现气体混合物的特性分析，分辨率为 0.01 原子质量单位。
