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使用含氧化钕纳米颗粒的甲基丙烯酸对生物相容性水凝胶镜片进行表征

Characterization of Biocompatible Hydrogel Lenses Using Methacrylic Acid with Neodymium Oxide Nanoparticles.

作者信息

Lee Min-Jae, Park Seon-Young, Sung A-Young

机构信息

Department of Optometry, Jeju Tourism University, Jeju 63063, Korea.

Department of Optometry & Vision Science, Daegu Catholic University, Gyeongsan 38430, Korea.

出版信息

Polymers (Basel). 2021 May 14;13(10):1575. doi: 10.3390/polym13101575.

DOI:10.3390/polym13101575
PMID:34069015
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8156141/
Abstract

We prepared hydrogel contact lenses containing nanoparticles of neodymium oxide and methacrylic acid (MA) to investigate their effect on the physical and chemical properties of the lens. Neodymium oxide nanoparticles improved the tensile strength without affecting wettability. The tensile strength, wettability, and light transmittance were all increased when MA was added in a specific ratio. To confirm the safety of the newly used nanoparticles, test on absorbance, eluate, and pH change were conducted and it was found that the safety level was satisfactory. In conclusion, it was confirmed that durable contact lenses can be manufactured with neodymium oxide nanoparticles, and most of the basic elements of the lens such as transparency, strength, and wettability could be improved using MA, which is a hydrophilic material. It is believed that the study will be helpful as part of basic research to use new materials.

摘要

我们制备了含有氧化钕纳米颗粒和甲基丙烯酸(MA)的水凝胶隐形眼镜,以研究它们对镜片物理和化学性质的影响。氧化钕纳米颗粒提高了拉伸强度,而不影响润湿性。当以特定比例添加MA时,拉伸强度、润湿性和透光率均有所提高。为确认新使用的纳米颗粒的安全性,进行了吸光度、洗脱液和pH值变化测试,结果发现安全水平令人满意。总之,已证实可以用氧化钕纳米颗粒制造耐用的隐形眼镜,并且使用亲水性材料MA可以改善镜片的大多数基本特性,如透明度、强度和润湿性。相信该研究作为使用新材料的基础研究的一部分将有所帮助。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ae/8156141/75ef508f945e/polymers-13-01575-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ae/8156141/3568b5b9e852/polymers-13-01575-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ae/8156141/fc2c1253cd17/polymers-13-01575-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ae/8156141/292b1e54fa5b/polymers-13-01575-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ae/8156141/b4476942facb/polymers-13-01575-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ae/8156141/30f2fb1d82ad/polymers-13-01575-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ae/8156141/77e1da9882f0/polymers-13-01575-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ae/8156141/75ef508f945e/polymers-13-01575-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ae/8156141/3568b5b9e852/polymers-13-01575-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ae/8156141/fc2c1253cd17/polymers-13-01575-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ae/8156141/292b1e54fa5b/polymers-13-01575-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ae/8156141/b4476942facb/polymers-13-01575-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ae/8156141/30f2fb1d82ad/polymers-13-01575-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ae/8156141/77e1da9882f0/polymers-13-01575-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ae/8156141/75ef508f945e/polymers-13-01575-g007.jpg

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