Department of Analytical Chemistry, Iuliu Hațieganu University of Medicine and Pharmacy, 4 Louis Pasteur Street, 400349 Cluj-Napoca, Romania.
Molecules. 2021 May 27;26(11):3200. doi: 10.3390/molecules26113200.
Food safety and quality control pose serious issues to food industry and public health domains, in general, with direct effects on consumers. Any physical, chemical, or biological unexpected or unidentified food constituent may exhibit harmful effects on people and animals from mild to severe reactions. According to the World Health Organization (WHO), unsafe foodstuffs are especially dangerous for infants, young children, elderly, and chronic patients. It is imperative to continuously develop new technologies to detect foodborne pathogens and contaminants in order to aid the strengthening of healthcare and economic systems. In recent years, peptide-based sensors gained much attention in the field of food research as an alternative to immuno-, apta-, or DNA-based sensors. This review presents an overview of the electrochemical biosensors using peptides as molecular bio-recognition elements published mainly in the last decade, highlighting their possible application for rapid, non-destructive, and in situ analysis of food samples. Comparison with peptide-based optical and piezoelectrical sensors in terms of analytical performance is presented. Methods of foodstuffs pretreatment are also discussed.
食品安全和质量控制一般来说对食品工业和公共卫生领域构成严重问题，直接影响消费者。任何物理、化学或生物的意外或未识别的食物成分都可能对人和动物产生从轻微到严重的反应。根据世界卫生组织（WHO）的说法，不安全的食品对婴儿、幼儿、老年人和慢性病患者尤其危险。为了加强医疗保健和经济体系，必须不断开发新技术来检测食源性病原体和污染物。近年来，基于肽的传感器作为免疫、适体或 DNA 传感器的替代品，在食品研究领域引起了广泛关注。本综述主要介绍了过去十年中发表的用作分子生物识别元件的电化学生物传感器的概述，强调了它们在快速、无损和原位分析食品样品方面的潜在应用。还比较了基于肽的光学和压电传感器在分析性能方面的差异。讨论了食品预处理方法。
