Zhong Lishi, Zhang Lili, Li Yimeng, Liang Xue, Kong Lu, Shen Xiaobing, Wu Tianshu
Key Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China.
School of Public Health, Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan 250117, China.
Int J Environ Res Public Health. 2021 May 27;18(11):5768. doi: 10.3390/ijerph18115768.
Along with the rapid development of nanotechnology, the biosafety of quantum dots (QDs), a widely used kind of nanoparticles, has grabbed the attentions of researchers, because QDs have excellent and unique optical properties that other commonly used nanoparticles, like walled carbon nanotubes, do not have. The understanding of the toxicity of QDs is an important premise for their application in wider fields, including biology and medicine. This study sought to analyze scientific publications on the toxicity of QDs and to construct a bibliometric model for qualitative and quantitative evaluation of these publications over the past decade, which visually presented the status quo and future development trend on the toxicological study of QDs. A search for data using the triple blind method revealed that, as of 31 December 2018, there were 5269 papers published on the toxicity of QDs. RSC ADVANCES (5-year IF, 3.096) ranked first in the number of publications. China had the largest number of publications (2233) and the highest H-index (119), but the United States was still the leading country with regards to the quality of the research. LIU Y (106 publications) published the most papers, while Hardman R (304 co-citations) had the most co-citations. The keyword "walled carbon nanotube" ranked first in the research frontier. The findings not only determine a development trend of the toxicological study of QDs, but also identify further research directions in this field.
随着纳米技术的迅速发展，量子点（QDs）作为一种广泛应用的纳米粒子，其生物安全性已引起研究人员的关注，因为量子点具有其他常用纳米粒子（如壁式碳纳米管）所不具备的优异且独特的光学性质。了解量子点的毒性是其在包括生物学和医学在内的更广泛领域应用的重要前提。本研究旨在分析关于量子点毒性的科学出版物，并构建一个文献计量模型，用于对过去十年这些出版物进行定性和定量评估，直观呈现量子点毒理学研究的现状和未来发展趋势。采用三盲法搜索数据发现，截至2018年12月31日，已发表5269篇关于量子点毒性的论文。《RSC ADVANCES》（5年影响因子为3.096）在出版物数量上排名第一。中国的出版物数量最多（2233篇），H指数最高（119），但在研究质量方面，美国仍是领先国家。刘Y（106篇出版物）发表的论文最多，而哈德曼·R（304次共被引）的共被引次数最多。关键词“壁式碳纳米管”在研究前沿排名第一。这些发现不仅确定了量子点毒理学研究的发展趋势，还确定了该领域进一步的研究方向。
