Ramos-Nino Maria E, Fitzpatrick Daniel M, Eckstrom Korin M, Tighe Scott, Dragon Julie A, Cheetham Sonia
Department of Microbiology, Immunology, and Pharmacology, School of Medicine, St. George's University, West Indies, Grenada.
Department of Pathobiology, School of Veterinary Medicine, St. George's University, West Indies, Grenada.
Animals (Basel). 2021 May 27;11(6):1571. doi: 10.3390/ani11061571.
Bats are capable of asymptomatically carrying a diverse number of microorganisms, including human pathogens, due to their unique immune system. Because of the close contact between bats and humans, there is a possibility for interspecies transmission and consequential disease outbreaks. Herein, high-throughput sequencing was used to determine the kidney-associated microbiome of a bat species abundant in Grenada, West Indies, spp. Results indicate that the kidney of these bats can carry potential human pathogens. An endogenous retrovirus, endogenous retrovirus isolate 824, phylogenetically related to betaretroviruses from rodents and New World primates, was also identified.
由于其独特的免疫系统,蝙蝠能够无症状地携带多种微生物,包括人类病原体。由于蝙蝠与人类的密切接触,存在跨物种传播及随之而来的疾病爆发的可能性。在此,利用高通量测序来确定西印度群岛格林纳达大量存在的一种蝙蝠物种—— 种的与肾脏相关的微生物群。结果表明,这些蝙蝠的肾脏能够携带潜在的人类病原体。还鉴定出一种内源性逆转录病毒,即内源性逆转录病毒分离株824,它在系统发育上与来自啮齿动物和新大陆灵长类动物的β逆转录病毒相关。