School of Sport and Exercise Sciences, Division of Natural Sciences, University of Kent, Canterbury CT2 7PE, UK.
Nutrients. 2021 May 24;13(6):1789. doi: 10.3390/nu13061789.
There has been a great deal of interest in bovine colostrum within sports nutrition over the last 25 years. Studies have investigated the effects on body composition, physical performance, recovery, gut damage and permeability, immune function, and illness risk. This narrative review considers available evidence in each of these areas. Although some studies have shown protection against performance decrements caused by periods of intensified training, there is limited evidence for effects on body composition and physical performance. There is stronger evidence for benefit on gut permeability and damage markers and on immune function and illness risk, especially during periods of intensified training. The balance of available evidence for gut permeability and illness risk is positive, but further research is required to fully determine all mechanisms responsible for these effects. Early suggestions that supplementation with bovine colostrum products could increase systemic IGF-1 levels are not supported by the balance of available evidence examining a range of doses over both short- and long-term periods. Nevertheless, dose-response studies would be valuable for determining the minimum efficacious dose, although this is complicated by variability in bioactivity between products, making any dose-response findings applicable only to the specific products used in such studies.
在过去的 25 年中,牛初乳在运动营养领域引起了极大的关注。研究已经调查了其对身体成分、身体表现、恢复、肠道损伤和通透性、免疫功能和疾病风险的影响。本综述考虑了这些领域的现有证据。尽管一些研究表明,牛初乳可以预防因强化训练而导致的身体表现下降,但对其对身体成分和身体表现的影响的证据有限。对肠道通透性和损伤标志物以及免疫功能和疾病风险的有益作用的证据更强,尤其是在强化训练期间。目前对于肠道通透性和疾病风险的证据是积极的,但需要进一步的研究来确定所有这些作用的机制。早期有研究表明,牛初乳产品的补充可以增加系统 IGF-1 水平,但目前检查了一系列剂量的短期和长期研究结果并不支持这一观点。然而,剂量反应研究对于确定最小有效剂量是有价值的,尽管由于产品之间的生物活性存在差异,这使得任何剂量反应的发现仅适用于这些研究中使用的特定产品,这使得情况变得复杂。