Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AD, UK.
Department of R&D, PanTheryx Inc., Boulder, CO 80301, USA.
Nutrients. 2021 Jan 18;13(1):265. doi: 10.3390/nu13010265.
Colostrum is the milk produced during the first few days after birth and contains high levels of immunoglobulins, antimicrobial peptides, and growth factors. Colostrum is important for supporting the growth, development, and immunologic defence of neonates. Colostrum is naturally packaged in a combination that helps prevent its destruction and maintain bioactivity until it reaches more distal gut regions and enables synergistic responses between protective and reparative agents present within it. Bovine colostrum been used for hundreds of years as a traditional or complementary therapy for a wide variety of ailments and in veterinary practice. Partly due to concerns about the side effects of standard Western medicines, there is interest in the use of natural-based products of which colostrum is a prime example. Numerous preclinical and clinical studies have demonstrated therapeutic benefits of bovine colostrum for a wide range of indications, including maintenance of wellbeing, treatment of medical conditions and for animal husbandry. Articles within this Special Issue of cover the effects and use bovine colostrum and in this introductory article, we describe the main constituents, quality control and an overview of the use of bovine colostrum in health and disease.
初乳是婴儿出生后头几天产生的奶，含有高水平的免疫球蛋白、抗菌肽和生长因子。初乳对支持新生儿的生长、发育和免疫防御很重要。初乳自然包装在一种组合中，有助于防止其破坏，并保持生物活性，直到它到达更远的肠道区域，并使其中存在的保护和修复剂之间产生协同反应。牛初乳作为一种传统或补充疗法，已经使用了数百年，用于治疗各种疾病和兽医实践。部分由于对标准西药副作用的担忧，人们对天然产品的使用产生了兴趣，牛初乳就是一个很好的例子。大量的临床前和临床研究表明，牛初乳对广泛的适应症具有治疗益处，包括维持健康、治疗疾病和用于畜牧业。本特刊中的文章涵盖了牛初乳的作用和用途，在这篇介绍性文章中，我们描述了牛初乳的主要成分、质量控制以及在健康和疾病中的应用概述。
