Department of Biological Sciences, Faculty of Physical Culture in Gorzów Wielkopolski, Poznan University of Physical Education, Estkowskiego 13, 66-400 Gorzów Wielkopolski, Poland.
Department of Pathology & Laboratory Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ONT K1H 8M5, Canada.
Nutrients. 2022 Jun 17;14(12):2512. doi: 10.3390/nu14122512.
Bovine colostrum (BC) contains a myriad of bioactive molecules that are renowned for possessing unique medicinal benefits in children and adults, and BC supplements are considered safe and cost-effective options to manage/prevent the incidence of upper respiratory tract infections and gut-related problems in athletes. In this review, we will try to answer the question: How will BC supplementation ameliorate gut permeability problems among athletes?
Literature searches were performed using PRISMA guidance to identify studies assessing the influence of BC supplements on gut permeability. Studies were selected using four databases: PubMed, Web of Science, Scopus, and EBSCO, and a total number of 60 articles were retrieved by using appropriate keywords.
Nine studies were selected that met the eligibility criteria for this review. The data analysis revealed that vigorous exercise profoundly increases intestinal permeability, and BC supplementation helps to reverse gut permeability in athletes.
BC supplementation may be highly beneficial in improving gut permeability in athletes. However, well-designed, placebo-controlled, and randomized studies are needed to evaluate the long-term safety and efficacy and to determine the optimal dose schedules of BC supplementation in high-performance athletes.
牛初乳（BC）含有多种生物活性分子，以其在儿童和成人中具有独特的药用功效而闻名，BC 补充剂被认为是安全且具有成本效益的选择，可用于管理/预防运动员上呼吸道感染和与肠道相关的问题的发生。在本次综述中，我们将尝试回答以下问题：BC 补充剂如何改善运动员的肠道通透性问题？
我们按照 PRISMA 指南进行文献检索，以确定评估 BC 补充剂对肠道通透性影响的研究。研究使用四个数据库（PubMed、Web of Science、Scopus 和 EBSCO）进行选择，使用适当的关键词共检索到 60 篇文章。
符合本综述纳入标准的有 9 项研究。数据分析表明，剧烈运动显著增加肠道通透性，而 BC 补充剂有助于逆转运动员的肠道通透性。
BC 补充剂可能对改善运动员的肠道通透性非常有益。然而，需要进行精心设计、安慰剂对照和随机研究，以评估 BC 补充剂在高水平运动员中的长期安全性和疗效，并确定最佳的 BC 补充剂剂量方案。
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