Lupi Saturnino Marco, Torchia Mirko, Rizzo Silvana
Department of Clinical Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.
Materials (Basel). 2021 May 24;14(11):2798. doi: 10.3390/ma14112798.
The discovery of osseointegration of titanium implants revolutionized the dental prosthesis field. Traditionally, implants have a surface that is processed by additive or subtractive techniques, which have positive effects on the osseointegration process by altering the topography. In the last decade, innovative implant surfaces have been developed, on which biologically active molecules have been immobilized with the aim of increasing stimulation at the implant-biological tissue interface, thus favoring the quality of osseointegration. Among these molecules, some are normally present in the human body, and the techniques for the immobilization of these molecules on the implant surface have been called Biochemical Modification of Titanium Surfaces (BMTiS). Different techniques have been described in order to immobilize those biomolecules on titanium implant surfaces. The aim of the present paper is to present evidence, available from in vivo studies, about the effects of biochemical modification of titanium oral implants on osseointegration.
钛植入物骨结合的发现彻底改变了牙科修复领域。传统上，植入物的表面是通过加法或减法技术处理的，这些技术通过改变表面形貌对骨结合过程产生积极影响。在过去十年中，已开发出创新的植入物表面，上面固定了生物活性分子，目的是增加对植入物 - 生物组织界面的刺激，从而有利于骨结合的质量。在这些分子中，有些通常存在于人体中，将这些分子固定在植入物表面的技术被称为钛表面生化改性（BMTiS）。为了将这些生物分子固定在钛植入物表面，人们描述了不同的技术。本文的目的是展示来自体内研究的证据，说明钛口腔植入物的生化改性对骨结合的影响。
