Huddy S P, Shorthouse A J, Marks C G
Royal Surrey County Hospital, Guildford.
Ann R Coll Surg Engl. 1988 Jan;70(1):40-3.
Forty two consecutive patients who underwent surgery for an obstructing carcinoma of the left colon over a 5 year period were studied retrospectively. Twelve patients underwent an initial defunctioning procedure with no hospital deaths but with four deaths after a mean follow-up of 25 months. Of the 30 patients who had a primary tumour resection, 7 died during the first hospital admission and a further 4 during a mean follow-up period of 23.7 months. The hospital mortality following primary resection was related to the site and timing of the anastomosis. During the first hospital admission 3 of 5 patients died after colocolic anastomosis, 3 of 10 died following ileocolic anastomosis, but only 1 of 15 died in those who did not have a primary anastomosis performed. The mean hospital stay of patients undergoing a delayed resection was 41 (s.e. (mean) 2.8) days compared to 24 (s.e. (mean) 2.8) days in those undergoing a primary resection. Primary tumour resection with a delayed anastomosis is recommended on the basis of these findings.
对连续42例在5年期间因左半结肠癌梗阻接受手术的患者进行了回顾性研究。12例患者最初接受了转流手术,无医院死亡病例,但平均随访25个月后有4例死亡。在30例行原发性肿瘤切除的患者中,7例在首次住院期间死亡,另有4例在平均23.7个月的随访期内死亡。原发性切除后的医院死亡率与吻合部位和时机有关。在首次住院期间,5例行结肠结肠吻合术的患者中有3例死亡,10例行回结肠吻合术的患者中有3例死亡,但在未进行原发性吻合术的15例患者中仅1例死亡。接受延迟切除的患者平均住院时间为41(标准误(均值)2.8)天,而接受原发性切除的患者为24(标准误(均值)2.8)天。基于这些发现,建议行原发性肿瘤切除并延迟吻合。