生活质量和人格特征与青少年代谢综合征的关系：一项队列研究。
The association of quality of life and personality characteristics with adolescent metabolic syndrome: a cohort study.
机构信息
Clinical Epidemiology and Biostatistics Department, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, Key Laboratory of Pediatrics in Chongqing, China International Science and Technology Cooperation Center of Child Development and Critical Disorders, 136 2nd Street, Yuzhong District, Chongqing, 400016, China.
Disease Control and Prevention Center of Jiulongpo District, Chongqing, China.
出版信息
Health Qual Life Outcomes. 2021 Jun 8;19(1):160. doi: 10.1186/s12955-021-01797-7.
BACKGROUND
An increased prevalence of adolescent metabolic syndrome (MS) is associated with adulthood cardiovascular diseases. This study aimed to explore the potential relationship of quality of life (QoL) and personality traits with adolescent MS.
METHODS
A total of 1961 participants from Chongqing with an average age of 11.68 years old from a cohort study established in 2014 and followed up through 2019 were included. QoL information, Eysenck's personality questionnaire and MS components were collected.
RESULTS
A higher QoL domain score of physical activity ability (PAA) was a protective factor for both MS and MS score (all P < 0.01), which was mainly negatively correlated with the MS components of central obesity, diastolic blood pressure (DBP) and triglyceride levels, as well as positively correlated with high density lipoprotein cholesterol (HDL-C) level. The total QoL score was negatively correlated with triglyceride levels and positively correlated with DBP (all P < 0.01). High extraversion personality score was a protective factor against adolescent MS (P = 0.04) and MS score (P < 0.05), which were mainly negatively correlated with the MS components of waist circumference, systolic blood pressure and TGs, and positively correlated with HDL-C (all P ≤ 0.01).
CONCLUSIONS
QoL score and extraversion personality score were independent protective factors against both MS prevalence and MS score, suggesting that community intervention to improve the QoL and psychological health of children are essential.
背景
青少年代谢综合征（MS）的患病率增加与成年期心血管疾病有关。本研究旨在探讨生活质量（QoL）和人格特质与青少年 MS 的潜在关系。
方法
本研究纳入了 2014 年建立并于 2019 年随访的重庆队列研究中的 1961 名平均年龄为 11.68 岁的参与者。收集了 QoL 信息、艾森克人格问卷和 MS 成分。
结果
较高的身体活动能力（PAA）领域 QoL 评分是 MS 和 MS 评分的保护因素（均 P<0.01），主要与中心性肥胖、舒张压（DBP）和甘油三酯水平呈负相关，与高密度脂蛋白胆固醇（HDL-C）水平呈正相关。总体 QoL 评分与甘油三酯水平呈负相关，与 DBP 呈正相关（均 P<0.01）。高外向性人格评分是青少年 MS（P=0.04）和 MS 评分（P<0.05）的保护因素，主要与腰围、收缩压和 TGs 呈负相关，与 HDL-C 呈正相关（均 P≤0.01）。
结论
QoL 评分和外向性人格评分是 MS 患病率和 MS 评分的独立保护因素，这表明改善儿童的 QoL 和心理健康的社区干预至关重要。
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