细颗粒物暴露对 10-13 岁青少年变应性鼻炎的影响：来自中国重庆的一项横断面研究。
The effect of fine particulate matter exposure on allergic rhinitis of adolescents aged 10-13 years: A cross-sectional study from Chongqing, China.
机构信息
Department of Clinical Epidemiology and Biostatistics, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Health and Nutrition, Chongqing, China.
Department of Epidemiology, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
出版信息
Front Public Health. 2022 Oct 25;10:921089. doi: 10.3389/fpubh.2022.921089. eCollection 2022.
BACKGROUND
Allergic rhinitis (AR) has become a tremendous disease burden worldwide. Only a few studies have explored the effects of environmental exposure on the prevalence of AR in children in China.
METHODS
In the present study, we investigated the associations of environmental exposure (including fine particulate matter (PM), air humidity, temperature, and passive smoking) with AR in adolescents aged 10-13 years in Chongqing. Data from 4,146 participants in urban and rural areas between March 2019 and May 2019 were collected.
RESULTS
The overall prevalence of AR was 17.50% in adolescents. After adjusting for other covariates, AR was positively correlated with the annual mean PM concentration, monthly mean PM concentration and air temperature, and negatively related to air humidity. Furthermore, the annual mean PM was positively associated with the risk of AR after adjusting for air temperature and humidity. Passive smoking (PS) was marginally associated with a high risk of AR.
CONCLUSION
High PM exposure, high air temperature, and low air humidity were associated with a high risk of AR in adolescents. Our findings have potential implications for public health strategies and interventions aimed at reducing the burden of AR in adolescents.
背景
变应性鼻炎（AR）已成为全球巨大的疾病负担。只有少数研究探讨了环境暴露对中国儿童 AR 患病率的影响。
方法
本研究调查了环境暴露（包括细颗粒物（PM）、空气湿度、温度和被动吸烟）与重庆 10-13 岁青少年 AR 之间的关联。2019 年 3 月至 5 月期间在城乡地区收集了 4146 名参与者的数据。
结果
青少年的 AR 总体患病率为 17.50%。在调整其他协变量后，AR 与年平均 PM 浓度、月平均 PM 浓度和空气温度呈正相关，与空气湿度呈负相关。此外，在调整温度和湿度后，年平均 PM 与 AR 的风险呈正相关。被动吸烟（PS）与 AR 的高风险呈边际相关。
结论
高 PM 暴露、高空气温度和低空气湿度与青少年 AR 的高风险相关。我们的研究结果为旨在减轻青少年 AR 负担的公共卫生策略和干预措施提供了潜在意义。
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