Ghelejkhani Arezoo, Nadalizadeh Sareh, Rajabi Mansoureh
Department of Pediatric Dentistry, Shahid Beheshti University of Medical Science, Tehran, Iran.
Private Office, Tehran, Iran.
Dent Res J (Isfahan). 2021 Mar 17;18:20. eCollection 2021.
Laser therapy, along with the use of fluoridated compounds is a novel technique suggested for caries prevention. Casein phosphopeptide amorphous calcium phosphate (CPP-ACP) is another product suggested for this purpose. This study compared the effect of CPP-ACP and fluoride with/without Erbium, chromium-doped yttrium, scandium, gallium, and garnet laser irradiation on enamel microhardness of permanent teeth.
This experimental study evaluated 35 extracted third molars. The teeth were decoronated, and the crowns were split into buccal and lingual halves. The samples were randomly divided into seven groups ( = 10) of GC Tooth Mousse, MI Paste Plus, laser, fluoride varnish, laser + GC Tooth Mousse, laser + MI Paste Plus, and laser + fluoride varnish. The baseline microhardness was measured before the intervention. After the intervention, the samples were kept in artificial saliva for 1 h and were then immersed in the demineralizing solution for 3 h followed by 21 h of immersion in the remineralizing solution for a total period of 12 days. Finally, the teeth were kept in the remineralizing solution for 2 more days. The secondary microhardness of the teeth was then measured. Data were analyzed using the Shapiro-Wilk test, two-way ANOVA, and Tukey's Honestly Significant Difference test.
The fluoride varnish (14.31%) and laser + fluoride varnish (18.79%) groups experienced minimum reduction in microhardness, while the GC Tooth Mousse group experienced maximum reduction in microhardness (91.64%) ( < 0.001). Laser irradiation before the application of remineralizing agents increased the microhardness only in laser + GC Tooth Mousse group ( < 0.001).
Fluoride varnish increased the enamel microhardness, while GC Tooth Mousse had no such effect. Laser therapy before the application of remineralizing agents did not significantly enhance enamel resistance to demineralization.
激光治疗以及使用含氟化合物是一种新提出的预防龋齿的技术。酪蛋白磷酸肽无定形磷酸钙（CPP - ACP）是为此目的而提出的另一种产品。本研究比较了CPP - ACP和氟化物在有/无铒、铬掺杂钇、钪、镓和石榴石激光照射情况下对恒牙牙釉质显微硬度的影响。
本实验研究评估了35颗拔除的第三磨牙。去除牙冠，将牙冠分成颊侧和舌侧两半。样本被随机分为七组（每组n = 10），分别为GC护齿泡沫、MI糊剂加强型、激光、氟化漆、激光 + GC护齿泡沫、激光 + MI糊剂加强型以及激光 + 氟化漆。在干预前测量基线显微硬度。干预后将样本置于人工唾液中1小时，然后浸入脱矿溶液中3小时，接着再浸入再矿化溶液中21小时，总共持续12天。最后，将牙齿再置于再矿化溶液中2天。然后测量牙齿的二次显微硬度。数据采用夏皮罗 - 威尔克检验、双向方差分析和图基诚实显著性差异检验进行分析。
氟化漆组（14.31%）和激光 + 氟化漆组（18.79%）的显微硬度降低最少，而GC护齿泡沫组的显微硬度降低最多（91.64%）（P < 0.001）。在应用再矿化剂之前进行激光照射仅在激光 + GC护齿泡沫组中增加了显微硬度（P < 0.001）。
氟化漆增加了牙釉质的显微硬度，而GC护齿泡沫没有这种效果。在应用再矿化剂之前进行激光治疗并未显著增强牙釉质对脱矿的抵抗力。
