Li Chunlei, Sun Feng
Department of Gastroenterology, Jiaozhou Central Hospital, Jiaozhou, China.
Department of Colorectal and Anal Surgery, The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou, China.
Front Chem. 2021 May 31;9:696906. doi: 10.3389/fchem.2021.696906. eCollection 2021.
In recent years, antibiotic-resistant bacteria caused by antibiotic abuse in the medical industry have become a new environmental pollutant that endangers public health. Therefore, it is necessary to establish a detection method for evaluating drug-resistant bacteria. In this work, we used as a target model and proposed a method to evaluate its drug resistance for three antibiotics. Graphene dispersion was used to co-mix with cells for the purpose of increasing the current signal. This electrochemical-based sensor allows the evaluation of the activity of on the electrode surface. When antibiotics were present, the electrocatalytic reduction signal was diminished because of the reduced activity of . Based on the difference in the electrochemical reduction signal, we can evaluate the antibiotic resistance of different strains.
近年来,医疗行业抗生素滥用导致的耐药菌已成为一种危害公众健康的新型环境污染物。因此,有必要建立一种评估耐药菌的检测方法。在这项工作中,我们以[具体细菌名称未给出]为目标模型,提出了一种评估其对三种抗生素耐药性的方法。为了增加电流信号,使用石墨烯分散体与[具体细菌名称未给出]细胞共混。这种基于电化学的传感器能够评估[具体细菌名称未给出]在电极表面的活性。当存在抗生素时,由于[具体细菌名称未给出]活性降低,电催化还原信号减弱。基于电化学还原信号的差异,我们可以评估不同[具体细菌名称未给出]菌株的抗生素耐药性。