Department of Experimental & Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA.
Department of Psychiatry and Behavioral Sciences, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Pharmacogenomics. 2021 Jul;22(11):681-691. doi: 10.2217/pgs-2021-0058. Epub 2021 Jun 17.
Several healthcare organizations across Minnesota have developed formal pharmacogenomic (PGx) clinical programs to increase drug safety and effectiveness. Healthcare professional and student education is strong and there are multiple opportunities in the state for learners to gain workforce skills and develop advanced competency in PGx. Implementation planning is occurring at several organizations and others have incorporated structured utilization of PGx into routine workflows. Laboratory-based and translational PGx research in Minnesota has driven important discoveries in several therapeutic areas. This article reviews the state of PGx activities in Minnesota including educational programs, research, national consortia involvement, technology, clinical implementation and utilization and reimbursement, and outlines the challenges and opportunities in equitable implementation of these advances.
明尼苏达州的几家医疗机构已经制定了正式的药物基因组学（PGx）临床方案，以提高药物安全性和有效性。医疗保健专业人员和学生的教育水平较高，该州有多个机会让学习者获得劳动力技能，并在 PGx 方面发展高级能力。几家机构正在进行实施计划，其他机构已经将 PGx 的结构化使用纳入常规工作流程。明尼苏达州基于实验室和转化的 PGx 研究推动了多个治疗领域的重要发现。本文回顾了明尼苏达州 PGx 活动的现状，包括教育项目、研究、国家联盟参与、技术、临床实施和利用以及报销，并概述了公平实施这些进展所面临的挑战和机遇。
