Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Pediatric Specialists of Virginia, Fairfax, Virginia, USA.
Am J Gastroenterol. 2021 Sep 1;116(9):1954-1956. doi: 10.14309/ajg.0000000000001350.
The impact of the 2019 US Food and Drug Administration safety alert involving transmission of multidrug resistant organisms through fecal microbiota transplantation (FMT), and the COVID-19 pandemic on the use of FMT in children, is unknown.
A survey of pediatric gastroenterologists performing FMT for Clostridioides difficile infection was conducted.
Of 36 respondents, 17 (47%) and 30 (83%) changed their FMT practices related to the US Food and Drug Administration safety alert and COVID-19 pandemic, respectively, with 22 (61%) of programs halted.
The US Food and Drug Administration safety alert and COVID-19 pandemic have substantially influenced the availability and access of FMT for children.
2019 年美国食品和药物管理局（FDA）发布安全警报，称通过粪便微生物群移植（FMT）传播多药耐药菌，以及 COVID-19 大流行对儿童使用 FMT 的影响尚不清楚。
对进行艰难梭菌感染 FMT 的儿科胃肠病学家进行了调查。
在 36 名受访者中，分别有 17 名（47%）和 30 名（83%）因美国 FDA 安全警报和 COVID-19 大流行而改变了他们与 FMT 相关的做法，其中 22 个（61%）项目停止。
美国 FDA 的安全警报和 COVID-19 大流行极大地影响了儿童获得 FMT 的机会和途径。
