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血脑屏障:新型冠状病毒肺炎、大流行与细胞因子规范

Blood-Brain Barrier: COVID-19, Pandemics, and Cytokine Norms.

作者信息

Yarlagadda Atmaram, Preston Samuel L, Jeyadhas Rachel P, Lang Adam Edward, Hammamieh Rasha, Clayton Anita H

机构信息

Dr. Yarlagadda is the Installation Director of Psychological Health at McDonald Army Health Center in Fort Eustis, Virginia.

Dr. Preston is with Uniformed Services University of Health Sciences in Bethesda, Maryland.

出版信息

Innov Clin Neurosci. 2021 Jan 1;18(1-3):21-23. eCollection 2021 Jan-Mar.

Abstract

Neuropsychiatric manifestations of COVID-19 have become increasingly common in published literature as the COVID-19 pandemic continues to devastate the world. Morbidity and mortality associated with COVID-19 infection is driving recognition of the need for potential research in prevention, effective treatment, and reducing fatalities. In this article, we highlighted discussions and proposals previously reported in our series of articles on the subject of the blood-brain barrier to prevent both neurological and psychiatric manifestations of viral infection. The time for a rapid translational approach to bring point-of-care diagnostics and early prevention/treatment tools to practice is now, and it deserves immediate attention.

摘要

随着新冠疫情持续肆虐全球,新冠病毒感染的神经精神症状在已发表的文献中越来越常见。新冠病毒感染相关的发病率和死亡率促使人们认识到有必要在预防、有效治疗和降低死亡率方面开展潜在研究。在本文中,我们重点介绍了我们此前发表的一系列关于血脑屏障主题的文章中所报道的讨论和建议,以预防病毒感染的神经和精神症状。现在是时候采用快速转化方法将即时诊断和早期预防/治疗工具应用于实践了,这值得立即关注。

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