Department of Nursing, College of Nursing Science, Kyung Hee University, Seoul, 02447, South Korea.
Int J Hyg Environ Health. 2021 Jul;236:113798. doi: 10.1016/j.ijheh.2021.113798. Epub 2021 Jun 23.
In this study, a web-based behavioral intervention was designed, which aimed to reduce exposure to phthalate metabolites, bisphenol A, triclosan, and parabens in mothers with young children. A randomized controlled design with two groups was used to verify the effects of the intervention pre- and post-test. In total, 51 mothers participated in the study, categorizing 26 and 25 in the intervention and control groups, respectively. The web-based behavioral intervention focused on changes in diet, personal care products, and health behavior and reinforced behavior through encouragement. This program included an educational video, a game for locating endocrine disruptors at home, a method for locating facilities potentially emitting endocrine disruptors, resources, and a questions and answers mode. Data were collected from May 18 to June 30, 2020. Participants allocated to the intervention group were provided access to the behavioral intervention website via a computer or smartphone. Participants allocated to the control group were sent written information about endocrine disruptors via mail. For both the intervention and control groups, questionnaire results and maternal urine samples were assessed at baseline, during the intervention, and after one month. After the intervention, the urinary concentrations of mono (2-ethylhexyl) phthalate (MEHP), mono (2-ethyl-5-oxohexyl) phthalate (MEOHP), bisphenol A (BPA), methylparaben (MP), ethylparaben (EP), and propylparaben (PP) were found to be significantly decreased in the intervention group. Compared with the control group, the intervention group showed significantly decreased urinary geometric mean values of MEHP, MEOHP, BPA, MP, and PP after one month compared with those during the intervention (3.8%, 16.3%, 28.4%, 9.2%, and 24.4%, respectively). Hence, the web-based behavioral intervention was effective at reducing the exposure to endocrine disruptors in mothers with young children.
在这项研究中，设计了一种基于网络的行为干预措施，旨在减少有幼儿的母亲接触邻苯二甲酸代谢物、双酚 A、三氯生和对羟基苯甲酸酯。采用随机对照设计，分为两组，对干预前后的效果进行验证。共有 51 名母亲参与了这项研究，其中干预组 26 人，对照组 25 人。基于网络的行为干预措施主要集中在改变饮食、个人护理产品和健康行为，并通过鼓励来强化行为。该方案包括教育视频、在家中寻找内分泌干扰物的游戏、寻找潜在排放内分泌干扰物的设施的方法、资源以及问答模式。数据于 2020 年 5 月 18 日至 6 月 30 日收集。分配到干预组的参与者通过计算机或智能手机访问行为干预网站。分配到对照组的参与者通过邮件收到关于内分泌干扰物的书面信息。对于干预组和对照组，在基线、干预期间和一个月后评估问卷结果和产妇尿液样本。干预后，干预组尿液中邻苯二甲酸单（2-乙基己基）酯（MEHP）、邻苯二甲酸单（2-乙基-5-氧代己基）酯（MEOHP）、双酚 A（BPA）、甲基对羟基苯甲酸酯（MP）、乙基对羟基苯甲酸酯（EP）和丙基对羟基苯甲酸酯（PP）的浓度显著降低。与对照组相比，干预组一个月后的尿液中 MEHP、MEOHP、BPA、MP 和 PP 的几何均数分别比干预期间降低了 3.8%、16.3%、28.4%、9.2%和 24.4%。因此，基于网络的行为干预措施可有效降低幼儿母亲接触内分泌干扰物的水平。
