Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.
Biochemistry Laboratory, University Teaching Hospital of Yaoundé, Yaoundé, Cameroon.
BMC Oral Health. 2021 Jun 29;21(1):326. doi: 10.1186/s12903-021-01661-6.
Oral health is a frequently ignored aspect of global health in sub-Saharan patients. Periodontitis, a very frequent oral disease has been proven to be associated to development of the metabolic syndrome. This study aims to evaluate the relationship between periodontal disease and metabolic syndrome components in a sub-Saharan population.
We performed a cross sectional study in 3 Yaounde hospitals. Consenting adults aged 21 years and above were recruited. Participants who presented with a tooth loss of at least 50% or any condition which could alter values of biological and periodontal parameters (tobacco smoking, pregnancy, chronic kidney disease, cancer) were excluded. Metabolic syndrome elements (glycaemia, arterial pressure, HDL cholesterol, abdominal circumference, triglycerides) and periodontal variables were recorded (plaque and gingival index of Silness and Loe, periodontal pocket depth and clinical attachment loss). These variables were compared using Fisher's exact Test and odds ratio calculated with 95% confidence intervals.
The prevalence of periodontitis and metabolic syndrome were 43.4% and 10.8% respectively. Age (37.75 ± 13.25, P < 0.001) and poor accessory brushing methods were associated risk factors for development of periodontal disease. Sub-Saharan sindividuals with periodontitis had increased odds of having obesity (OR 11.1 [95% CI 3.97-31.03], P < 0.001) and low HDL (OR 4.58 [95% CI 1.79-11.70], P = 0.001) CONCLUSION: Our findings suggest an association between periodontal disease and metabolic syndrome in Sub-Saharan subjects. Increasing age and poor accessory brushing methods are associated risk indicators.
口腔健康是撒哈拉以南地区患者全球健康中经常被忽视的一个方面。牙周炎是一种非常常见的口腔疾病，已被证明与代谢综合征的发展有关。本研究旨在评估撒哈拉以南地区人群中牙周病与代谢综合征成分之间的关系。
我们在 3 家雅温得医院进行了一项横断面研究。同意参加的年龄在 21 岁及以上的成年人被招募。排除有至少 50%的牙齿缺失或任何可能改变生物和牙周参数值的条件的参与者（吸烟、怀孕、慢性肾脏病、癌症）。记录代谢综合征元素（血糖、动脉压、高密度脂蛋白胆固醇、腰围、甘油三酯）和牙周变量（Silness 和 Loe 的菌斑和牙龈指数、牙周袋深度和临床附着丧失）。使用 Fisher 确切检验比较这些变量，并计算 95%置信区间的比值比。
牙周炎和代谢综合征的患病率分别为 43.4%和 10.8%。年龄（37.75±13.25，P<0.001）和不良辅助刷牙方法是牙周病发展的相关危险因素。患有牙周炎的撒哈拉以南个体发生肥胖的几率增加（OR 11.1[95%CI 3.97-31.03]，P<0.001）和低 HDL（OR 4.58[95%CI 1.79-11.70]，P=0.001）。
我们的研究结果表明，撒哈拉以南地区人群中牙周病与代谢综合征之间存在关联。年龄增长和不良辅助刷牙方法是相关的危险因素。
