Del Riccio Marco, Boccalini Sara, Rigon Lisa, Biamonte Massimiliano Alberto, Albora Giuseppe, Giorgetti Duccio, Bonanni Paolo, Bechini Angela
Medical Specialization School in Hygiene and Preventive Medicine, University of Florence, 50134 Florence, Italy.
Department of Health Sciences, University of Florence, 50134 Florence, Italy.
Vaccines (Basel). 2021 Jun 10;9(6):633. doi: 10.3390/vaccines9060633.
Vaccination against SARS-CoV-2 represents an effective and safe tool to protect the population against the disease; however, COVID-19 vaccine hesitancy could be a major barrier to achieving herd immunity. Despite the severity of the current pandemic, the population's intention to get vaccinated against COVID-19 is still not clear. The aim of this study was to evaluate the intention to get vaccinated against COVID-19 among a convenience sample of the general population resident in Italy and the factors associated with hesitancy and acceptance of the vaccine in the context of the current pandemic before the rolling out of COVID-19 vaccines. An anonymous online survey was diffused among a general adult population living in Italy. Participants aged 18 or older and living in Italy were considered eligible. Incomplete questionnaires were excluded. Overall, 7605 valid questionnaires were collected. Most of the participants (81.9%) were inclined to get vaccinated; male sex (OR 1.38, 95% CI 1.12-1.71), a high level of trust in institutions (OR 3.93, 95% CI 2.04-7.83), and personal beliefs about high safety of COVID-19 vaccines (OR 56.33, 95% CI 31.57-105.87) were found to be among the significant predictors of COVID-19 acceptance. These data could help design larger studies to address the problem of COVID-19 vaccine hesitancy in the current pandemic.
接种新冠病毒疫苗是保护民众免受该疾病侵害的一种有效且安全的手段；然而，对新冠疫苗的犹豫可能是实现群体免疫的一个主要障碍。尽管当前疫情严峻，但民众接种新冠疫苗的意愿仍不明确。本研究的目的是评估意大利常住普通人群便利样本中接种新冠疫苗的意愿，以及在新冠疫苗推出之前当前疫情背景下与疫苗犹豫和接受相关的因素。一项匿名在线调查在居住在意大利的普通成年人群中展开。年龄在18岁及以上且居住在意大利的参与者被视为符合条件。不完整的问卷被排除。总体而言，共收集到7605份有效问卷。大多数参与者（81.9%）倾向于接种疫苗；男性（比值比1.38，95%置信区间1.12 - 1.71）、对机构的高度信任（比值比3.93，95%置信区间2.04 - 7.83）以及对新冠疫苗高安全性的个人信念（比值比56.33，95%置信区间3,157 - 105.87）被发现是接受新冠疫苗的显著预测因素。这些数据有助于设计更大规模的研究，以解决当前疫情中新冠疫苗犹豫的问题。
