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手部侵蚀性骨关节炎与银屑病关节炎的远端指间关节受累:保守治疗的地位

Hand Erosive Osteoarthritis and Distal Interphalangeal Involvement in Psoriatic Arthritis: The Place of Conservative Therapy.

作者信息

Poletto Elena, Tinazzi Ilaria, Marchetta Antonio, Smania Nicola, Rossato Elena

机构信息

Neuromotor and Cognitive Rehabilitation Research Center, Physical and Rehabilitation Medicine Section, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37129 Verona, Italy.

Rheumatology Unit, IRCCS Sacro Cuore Don Calabria, 37024 Negrar, Italy.

出版信息

J Clin Med. 2021 Jun 15;10(12):2630. doi: 10.3390/jcm10122630.

Abstract

Hand erosive osteoarthritis (HEOA) and Psoriatic Arthritis (PsA) with DIP involvement are common diseases affecting the hand. Both of them evolve with a progressive limitation in grip due to limited range of motion of the affected joints and stenosing tenosynovitis. Pharmacological options currently available (corticosteroids and clodronate or Idrossicloroquine) for the treatment of EHOA are mostly symptomatic and currently there are no effective drugs able to modify the course of the disease. In addition, data on drug effectiveness of PsA with DIP involvement are lacking. Conservative therapy should be considered in order to reduce pain and improve hand functionality. There are many studies debating a wide range of non-pharmacological intervention in the management of HEOA: joint protection program, range of motion and strengthening exercise, hand exercise with electromagnetic therapy, application of heat with paraffin wax or balneotherapy, occupational therapy and education. Concerning conservative treatment strategies to treat PsA, on the contrary, current evidence is still weak. Further research is needed to find the correct place of physical therapy to prevent stiffness and ankylosis due to the vicious circle of inflammation-pain-immobility-rigidity.

摘要

手部侵蚀性骨关节炎(HEOA)和累及远端指间关节(DIP)的银屑病关节炎(PsA)是影响手部的常见疾病。由于受累关节活动范围受限和狭窄性腱鞘炎,这两种疾病都会随着抓握能力的逐渐受限而发展。目前可用于治疗侵蚀性手部骨关节炎(EHOA)的药物选择(皮质类固醇、氯膦酸盐或羟氯喹)大多只是缓解症状,目前尚无能够改变疾病进程的有效药物。此外,关于累及DIP的PsA的药物疗效数据也很缺乏。应考虑采用保守治疗以减轻疼痛并改善手部功能。有许多研究探讨了在HEOA管理中广泛的非药物干预措施:关节保护计划、活动范围和强化锻炼、电磁疗法手部锻炼、石蜡热敷或温泉疗法、职业治疗和教育。相反,关于治疗PsA的保守治疗策略,目前的证据仍然不足。需要进一步研究以确定物理治疗在预防因炎症 - 疼痛 - 不动 - 僵硬恶性循环导致的僵硬和关节强直方面的正确作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2eed/8232729/0075b86400af/jcm-10-02630-g001.jpg

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