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药用植物生物活性特性研究

Study of the Biologically Active Properties of Medicinal Plant .

作者信息

Sukhikh Stanislav, Noskova Svetlana, Pungin Artem, Ivanova Svetlana, Skrypnik Liubov, Chupakhin Evgeny, Babich Olga

机构信息

Institute of Living Systems, Immanuel Kant Baltic Federal University, A. Nevskogo Street 14, 236016 Kaliningrad, Russia.

Department of Bionanotechnology, Kemerovo State University, Krasnaya Street 6, 650043 Kemerovo, Russia.

出版信息

Plants (Basel). 2021 Jun 16;10(6):1224. doi: 10.3390/plants10061224.

Abstract

The results of the studies have shown that to obtain an extract of a complex of biologically active substances of , ethyl alcohol (mass fraction of alcohol 70%) with a hydromodule of 1:5 should be used, and the extraction should be carried out for 60 min at a temperature of 60 °C. The investigated plant extracts with the complex of bioactive substances from the leaves and flowers are safe from the point of view of the content of heavy metals, pesticides, aflatoxin B1, radionuclides, as well as pathogenic and opportunistic microorganisms. It has been established that the extract contains rutin, hyperoside, ferulic acid, quercetin, kaempferol, disulphuretin, sulphurein, sulphurein, gallic acid, methyl gallate, pentagalloyl glucose, 3,3',4',5,6,7-hexahydroxyflavonone, 3,3',4',5,5',7-hexahydroxyflavonone, 3--α-L-rhamnofuranoside, 3,3',4',5,5',7-hexahydroxyflavulium(1+), 7--β-D glucopyranoside, and 3,3',4',7-tetrahydroxyflavonone. The tested extracts have anticancer, antigenotoxic, and antimicrobial (against , , , , ) properties. The high antioxidant status of the tested extracts was established; the antioxidant activity of the samples was 145.09 mg AA/g (AA-ascorbic acid).

摘要

研究结果表明,为了获得[具体植物名称]生物活性物质复合物的提取物,应使用体积分数为70%的乙醇,水与乙醇的比例为1:5,并且在60℃的温度下进行60分钟的提取。从重金属、农药、黄曲霉毒素B1、放射性核素以及致病和机会性微生物的含量来看,所研究的来自[具体植物名称]叶子和花朵的具有生物活性物质复合物的植物提取物是安全的。已经确定该提取物含有芦丁、金丝桃苷、阿魏酸、槲皮素、山奈酚、二硫苏糖醇、硫苏糖醇、没食子酸、没食子酸甲酯、五倍子酰葡萄糖、3,3',4',5,6,7 - 六羟基黄酮、3,3',4',5,5',7 - 六羟基黄酮、3 - α - L - 鼠李糖呋喃糖苷、3,3',4',5,5',7 - 六羟基黄鎓盐(1 +)、7 - β - D - 葡萄糖苷和3,3',4',7 - 四羟基黄酮。所测试的提取物具有抗癌、抗遗传毒性和抗菌(针对[具体微生物名称])特性。确定了所测试提取物具有较高的抗氧化状态;样品的抗氧化活性为145.09毫克抗坏血酸/克(AA - 抗坏血酸)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d47a/8235186/058639da4e83/plants-10-01224-g001.jpg

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