Department of Bionanotechnology, Kemerovo State University, Krasnaya Street 6, 650043 Kemerovo, Russia.
Institute of Living Systems, Immanuel Kant Baltic Federal University, A. Nevskogo Street 14, 236016 Kaliningrad, Russia.
Biomolecules. 2021 Feb 27;11(3):365. doi: 10.3390/biom11030365.
The results of the qualitative composition analysis of the dried biomass extracts of in vitro callus, cell suspension, and root cultures show that the main biologically active substances (BAS) in the medicinal plant, , are 6-C-(1-(4-hydroxyphenyl)ethyl)aromadendrin (25 mg, yield 0.21%), 2-(3,7-dihydroxy-2-(2-hydroxypropan-2-yl)-2,3-dihydrobenzofuran-5-yl)-6,7-dihydroxychroman-4-one (23 mg, yield 0.2%), 2-(3,4-dimethoxyphenyl)-5,7-dimethoxychroman-4-one (175 mg, yield 1.5%), 5,7-dihydroxy-2-(4-hydroxy-3-(2-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl)phenyl)-4H-chromen-4-one (45 mg, yield 0.5%), 5,6,7,8-tetrahydroxy-4-methoxyflavone (0.35 mg, 0.5%). BAS from the dried biomass extracts of in vitro callus, cell suspension, and root cultures of will be used for the production of pharmaceuticals and dietary supplements with antitumor, antimicrobial, and antioxidant effects.
体外愈伤组织、细胞悬浮液和根培养物的干燥生物量提取物的定性成分分析结果表明,药用植物中的主要生物活性物质(BAS)是 6-C-(1-(4-羟基苯基)乙基)芳樟素(25mg,产率 0.21%)、2-(3,7-二羟基-2-(2-羟基丙-2-基)-2,3-二氢苯并呋喃-5-基)-6,7-二羟基色满-4-酮(23mg,产率 0.2%)、2-(3,4-二甲氧基苯基)-5,7-二甲氧基色满-4-酮(175mg,产率 1.5%)、5,7-二羟基-2-(4-羟基-3-(2-(4-羟基苯基)-4-氧代-4H-色烯-6-基)苯基)-4H-色烯-4-酮(45mg,产率 0.5%)、5,6,7,8-四羟基-4-甲氧基黄酮(0.35mg,0.5%)。来自体外愈伤组织、细胞悬浮液和根培养物的干燥生物量提取物的 BAS 将用于生产具有抗肿瘤、抗菌和抗氧化作用的药物和膳食补充剂。