Cojocaru Anca, Marinescu Elena-Alexandra, Nica Oliviu, Ilinoiu Enio, Negrila Alina, Ciurea Marius-Eugen
Department of Dermatology, University of Medicine and Pharmacy of Craiova, Romania.
Department of Plastic Surgery, University of Medicine and Pharmacy of Craiova, Romania.
Curr Health Sci J. 2021 Jan-Mar;47(1):75-83. doi: 10.12865/CHSJ.47.01.12. Epub 2021 Mar 31.
Basal cell carcinoma (BCC) is the most common skin cancer. We conducted a retrospective study over a period of two years (2018-2019), on 214 patients from the Plastic Surgery clinic in order to identify the clinical and histopathological aspects of the disease: the case distribution according to sex, living environment, age, histopathological subtype, location. Results. The F/M ratio was of 1.03 in favour of women. The incidence was higher for patients from rural areas (55.14%). The most affected group age was between 70-80 years old, with 76 patients (35.51%). The most frequent histological type was nodular basal cell carcinoma (65.42%), followed by micronodular subtype (17.29%). We observed the association of basal cell carcinoma with a number of other conditions such as: high blood pressure (92 cases), diabetes (19 cases), chronic kidney disease (2 cases), liver disease (5 cases), epilepsy (2 cases). Correlating the histopathological subtype and the invasion of the edges of the surgical excision specimen, we noticed that edge invasion was present: in the case of nodular basal cell carcinoma (15.71%), micronodular subtype (43.24%), superficial subtype (50%), morpheaform subtype (40%). Dividing the cases by location, we highlighted the risk areas: nasal region (29.44%), cheek (10.75%), orbital region (13.55%), scalp (10.75%), auricular region (7.48%), forehead (8.41%), etc. Thus, 89.72% of cases were located on photo-exposed areas (head and neck). Patients from rural areas registered a higher number of cases both in photo-exposed and non-exposed areas.
基底细胞癌(BCC)是最常见的皮肤癌。我们对整形外科诊所的214名患者进行了为期两年(2018 - 2019年)的回顾性研究,以确定该疾病的临床和组织病理学特征:根据性别、生活环境、年龄、组织病理学亚型、发病部位的病例分布情况。结果。男女比例为1.03,女性患者居多。农村地区患者的发病率更高(55.14%)。受影响最严重的年龄组为70 - 80岁,有76名患者(35.51%)。最常见的组织学类型是结节性基底细胞癌(65.42%),其次是微结节亚型(17.29%)。我们观察到基底细胞癌与许多其他病症有关联,如:高血压(92例)、糖尿病(19例)、慢性肾病(2例)、肝病(5例)、癫痫(2例)。将组织病理学亚型与手术切除标本边缘的浸润情况相关联后,我们注意到存在边缘浸润的情况:在结节性基底细胞癌中为(15.71%),微结节亚型中为(43.24%),浅表亚型中为(50%),硬斑病样亚型中为(40%)。按发病部位划分病例后,我们突出了风险区域:鼻区(29.44%)、脸颊(10.75%)、眶区(13.55%)、头皮(10.75%)、耳区(7.48%)、前额(8.41%)等。因此,89.72%的病例位于光照暴露部位(头颈部)。农村地区患者在光照暴露部位和非光照暴露部位的病例数均较多。