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本文引用的文献

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EMBO Rep. 2020 Sep 3;21(9):e51278. doi: 10.15252/embr.202051278. Epub 2020 Aug 4.
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Impact of Precision Medicine on Drug Repositioning and Pricing: A Too Small to Thrive Crisis.精准医学对药物重新定位和定价的影响:规模过小难以蓬勃发展的危机
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Balancing animal welfare and assisted reproduction: ethics of preclinical animal research for testing new reproductive technologies.平衡动物福利与辅助生殖:用于测试新生殖技术的临床前动物研究的伦理问题
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From tokenism to meaningful engagement: best practices in patient involvement in an EU project.从表面文章到有意义的参与:患者参与欧盟项目的最佳实践
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Human tissues in a dish: The research and ethical implications of organoid technology.器官芯片技术的研究与伦理问题:培养皿中的人类组织
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Allogeneic Mesenchymal Stem Cells Stimulate Cartilage Regeneration and Are Safe for Single-Stage Cartilage Repair in Humans upon Mixture with Recycled Autologous Chondrons.同种异体间充质干细胞与回收的自体软骨颗粒混合后可刺激软骨再生,且对人类单阶段软骨修复是安全的。
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SCIENTIFIC COMMUNITY. Confronting stem cell hype.科学界。直面干细胞炒作。
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认识到干细胞研究的伦理含义:呼吁扩大研究范围。

Recognizing the ethical implications of stem cell research: A call for broadening the scope.

机构信息

Julius Center for Health Sciences and Primary Care, Department of Medical Humanities, University Medical Center Utrecht, 3508 GA Utrecht, the Netherlands.

Julius Center for Health Sciences and Primary Care, Department of Medical Humanities, University Medical Center Utrecht, 3508 GA Utrecht, the Netherlands.

出版信息

Stem Cell Reports. 2021 Jul 13;16(7):1656-1661. doi: 10.1016/j.stemcr.2021.05.021. Epub 2021 Jul 1.

DOI:10.1016/j.stemcr.2021.05.021
PMID:34214488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8282461/
Abstract

The ethical implications of stem cell research are often described in terms of risks, side effects, safety, and therapeutic value, which are examples of so-called hard impacts. Hard impacts are typically measurable and quantifiable. To understand the broader spectrum of ethical implications of stem cell research on science and society, it is equally important to recognize soft impacts. Soft impacts are the effects on behavior, experiences, actions, moral values, and social structures; these are often indirect effects of stem cell research. The combined notions of hard and soft impacts offer a broader way of thinking about the social and ethical implications of stem cell research and can help to steer stem cell research into a sociable desirable direction. Soft impacts enable researchers to become more aware of the broad range of significant implications involved in their work and deserve equal attention for understanding such ethical and societal effects of stem cell research.

摘要

干细胞研究的伦理影响通常从风险、副作用、安全性和治疗价值等方面来描述,这些都是所谓的硬影响的例子。硬影响通常是可测量和可量化的。为了更全面地了解干细胞研究对科学和社会的伦理影响,同样重要的是要认识到软影响。软影响是对行为、经验、行动、道德价值观和社会结构的影响;这些往往是干细胞研究的间接影响。硬影响和软影响的综合概念为我们提供了一种更广泛的思考干细胞研究的社会和伦理影响的方式,并有助于引导干细胞研究朝着一个理想的方向发展。软影响使研究人员更加意识到他们工作中涉及的广泛的重要影响,值得同等关注,以了解干细胞研究的这些伦理和社会影响。