狼疮性视网膜病变。模式、关联因素及预后。
Lupus retinopathy. Patterns, associations, and prognosis.
作者信息
Stafford-Brady F J, Urowitz M B, Gladman D D, Easterbrook M
机构信息
University of Toronto, Rheumatic Disease Unit, Wellesley Hospital, Ontario, Canada.
出版信息
Arthritis Rheum. 1988 Sep;31(9):1105-10. doi: 10.1002/art.1780310904.
In a prospective study of 550 patients with systemic lupus erythematosus (SLE), 41 were found to have retinopathy. Lupus retinopathy in the majority of cases consisted of a microangiopathy, with an excellent prognosis for vision. Five patients developed other complications that resulted in loss of visual acuity. Lupus retinopathy was associated with active SLE in 88% of patients and with lupus cerebritis in 73% of cases. Retinopathy in SLE was a marker of poor prognosis for survival.
在一项针对550例系统性红斑狼疮（SLE）患者的前瞻性研究中，发现41例患有视网膜病变。大多数情况下，狼疮性视网膜病变表现为微血管病变，视力预后良好。5例患者出现了导致视力丧失的其他并发症。88%的患者狼疮性视网膜病变与活动性SLE相关，73%的病例与狼疮性脑病相关。SLE中的视网膜病变是生存预后不良的一个指标。
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