Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald - Isle of Riems, Germany.
Center for Infection and Immunity and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, USA.
J Gen Virol. 2021 Jul;102(7). doi: 10.1099/jgv.0.001613.
Members of the family produce enveloped virions containing a linear negative-sense non-segmented RNA genome of about 9 kb. Bornaviruses are found in mammals, birds, reptiles and fish. The most-studied viruses with public health and veterinary impact are Borna disease virus 1 and variegated squirrel bornavirus 1, both of which cause fatal encephalitis in humans. Several orthobornaviruses cause neurological and intestinal disorders in birds, mostly parrots. Endogenous bornavirus-like sequences occur in the genomes of various animals. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family , which is available at ictv.global/report/bornaviridae.
该科病毒成员产生含有约 9kb 线性负义非节段 RNA 基因组的包膜病毒。正粘病毒科病毒存在于哺乳动物、鸟类、爬行动物和鱼类中。具有公共卫生和兽医影响的研究最多的病毒是博尔纳病病毒 1 和斑驳松鼠正粘病毒 1，两者都会导致人类致命脑炎。几种正粘病毒科病毒会导致鸟类、主要是鹦鹉的神经和肠道疾病。内源性正粘病毒样序列存在于各种动物的基因组中。这是国际病毒分类学委员会（ICTV）关于该科的报告摘要，可在 ictv.global/report/bornaviridae 上获得。
