Serviço de Medicina Interna, Centro Hospitalar de Setúbal - EPE - Setúbal, Portugal.
Unidade de Terapia Intensiva, Hospital Beatriz Ângelo - Lisboa, Portugal.
Rev Bras Ter Intensiva. 2021 Apr-Jun;33(2):325. doi: 10.5935/0103-507X.20210042.
COVID-19 was declared a pandemic by the World Health Organization on March 11, 2020. The clinical presentation is predominantly respiratory symptoms; however, in the current literature, several neurological manifestations associated with SARS-CoV-2 infection have been described. The authors present the clinical case of a 45-year-old man hospitalized for pneumonia with a positive test result for SARS-CoV-2, without a neurological history, who, on the sixteenth day of hospitalization, presented a sudden change in his state of consciousness accompanied by conjugated right gaze deviation and myoclonus of the face and thoracic region to the left, followed by generalized tonic-clonic seizures associated with persistent left hemiparesis. The present study highlights a positive RT-PCR test for SARS-CoV-2 in cerebrospinal fluid. The patient progressed with gradual improvement, and the outcome was favorable.
2020 年 3 月 11 日，世界卫生组织宣布 COVID-19 为大流行疾病。临床表现主要为呼吸道症状；然而，在目前的文献中，已经描述了与 SARS-CoV-2 感染相关的几种神经系统表现。作者介绍了一位 45 岁男性的临床病例，该患者因肺炎住院，SARS-CoV-2 检测结果呈阳性，无神经系统病史，在住院第 16 天，出现意识状态突然改变，伴有右侧凝视偏斜和面部及胸部左侧的面肌阵挛，随后出现全身性强直阵挛性癫痫发作，伴有持续性左侧偏瘫。本研究强调了 SARS-CoV-2 在脑脊液中的 RT-PCR 检测呈阳性。患者逐渐好转，结局良好。
