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与 COVID-19 相关的神经功能障碍。

NEUROLOGICAL DYSFUNCTION ASSOCIATED WITH COVID-19.

机构信息

Serviço de Medicina Interna, Centro Hospitalar de Setúbal - EPE - Setúbal, Portugal.

Unidade de Terapia Intensiva, Hospital Beatriz Ângelo - Lisboa, Portugal.

出版信息

Rev Bras Ter Intensiva. 2021 Apr-Jun;33(2):325. doi: 10.5935/0103-507X.20210042.

Abstract

COVID-19 was declared a pandemic by the World Health Organization on March 11, 2020. The clinical presentation is predominantly respiratory symptoms; however, in the current literature, several neurological manifestations associated with SARS-CoV-2 infection have been described. The authors present the clinical case of a 45-year-old man hospitalized for pneumonia with a positive test result for SARS-CoV-2, without a neurological history, who, on the sixteenth day of hospitalization, presented a sudden change in his state of consciousness accompanied by conjugated right gaze deviation and myoclonus of the face and thoracic region to the left, followed by generalized tonic-clonic seizures associated with persistent left hemiparesis. The present study highlights a positive RT-PCR test for SARS-CoV-2 in cerebrospinal fluid. The patient progressed with gradual improvement, and the outcome was favorable.

摘要

2020 年 3 月 11 日,世界卫生组织宣布 COVID-19 为大流行疾病。临床表现主要为呼吸道症状;然而,在目前的文献中,已经描述了与 SARS-CoV-2 感染相关的几种神经系统表现。作者介绍了一位 45 岁男性的临床病例,该患者因肺炎住院,SARS-CoV-2 检测结果呈阳性,无神经系统病史,在住院第 16 天,出现意识状态突然改变,伴有右侧凝视偏斜和面部及胸部左侧的面肌阵挛,随后出现全身性强直阵挛性癫痫发作,伴有持续性左侧偏瘫。本研究强调了 SARS-CoV-2 在脑脊液中的 RT-PCR 检测呈阳性。患者逐渐好转,结局良好。

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